5-Methoxy-3-pyridineboronic acid pinacol ester

CAS 445264-60-8C12H18BNO3Chemical Synthesis

5-Methoxy-3-pyridineboronic acid pinacol ester (CAS: 445264-60-8; Formula: C12H18BNO3) is a heterocyclic boronate ester with a molecular weight of 235.09 g/mol. This compound serves as a valuable building block in organic synthesis, particularly for applications involving Suzuki-Miyaura cross-coupling reactions. Its structure facilitates the formation of new carbon-carbon bonds, making it important in the development of complex organic molecules.

IUPAC: (3-Methoxypyridin-5-yl)boronic acid pinacol ester,(5-Methoxypyridin-3-yl)boronic acid pinacol ester,2-(5-Methoxypyridin-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane,3-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine,3-Methoxy-5-(pinacolboranato)pyridine,5-Methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) pyridine
Synonyms: 2-(5-Methoxypyridin-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane3-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine3-Methoxy-5-(pinacolboranato)pyridine5-Methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) pyridine(5-Methoxypyridin-3-yl)boronic acid pinacol ester

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5-Methoxy-3-pyridineboronic acid pinacol ester (C12H18BNO3) — chemical structure, CAS 445264-60-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Boronate EstersChemical SynthesisHeteroaryl Boronate EstersOrganometallic Reagents

01 /Applications

Suzuki-Miyaura Cross-Coupling Reactions

This boronate ester is primarily utilised as a coupling partner in Palladium-catalysed Suzuki-Miyaura reactions. It enables the efficient synthesis of biaryl compounds and other complex organic structures through the formation of C-C bonds with aryl or vinyl halides.

Heterocyclic Chemistry

As a heteroaryl boronate ester, it is instrumental in the synthesis of substituted pyridine derivatives. These are frequently found in pharmaceuticals and agrochemicals, highlighting its importance in medicinal chemistry research and development.

Organic Synthesis Building Block

Its defined structure and reactivity make it a versatile reagent for introducing a 5-methoxypyridin-3-yl moiety into target molecules. This is crucial for structure-activity relationship studies and the creation of novel chemical entities.

02 /Properties

Molecular weight	235.09
Empirical formula	C12H18BNO3
Assay	97%
Application	Heterocyclic boronate ester for use in Suzuki-Miyaura aryl-aryl cross-coupling.
Melting point	100-108 °C

03 /Identifiers & registry

CAS number

445264-60-8

MDL number

MFCD03412068

04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is 5-Methoxy-3-pyridineboronic acid pinacol ester used for?

5-Methoxy-3-pyridineboronic acid pinacol ester is primarily used as a reagent in Suzuki-Miyaura cross-coupling reactions for the synthesis of complex organic molecules, particularly those containing a 5-methoxypyridin-3-yl fragment.

What is the CAS number and formula for this compound?

The CAS number is 445264-60-8, and the empirical formula (Hill notation) is C12H18BNO3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this compound at an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

What are the safety and handling considerations for this chemical?

This compound is classified with a WGK (German Water Hazard Class) of 3, indicating it is hazardous to water. Appropriate personal protective equipment should be worn, and it should be handled in a well-ventilated area to avoid exposure.

How is 5-Methoxy-3-pyridineboronic acid pinacol ester packed, shipped, and exported?

Tech Serve Solutions packs, ships, and exports chemicals adhering to all relevant national and international regulations for hazardous materials. Specific packaging details are available upon request.

How can I request a sample or a quote for this product?

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