4-Methylumbelliferone
4-Methylumbelliferone (CAS: 90-33-5, C10H8O3, MW: 176.17) is an off-white to yellow crystalline powder recognised for its strong fluorescence in alkaline solutions. This coumarin derivative is a valuable intermediate and reagent. Its luminescent properties make it particularly useful in biochemical assays and as a fluorescent probe. Tech Serve Solutions supplies 4-Methylumbelliferone with a minimum assay of 98.0% (HPLC), suitable for research and chemical synthesis applications.
- IUPAC
- β-Methylumbelliferone,4-MU,7-Hydroxy-4-methylcoumarin
- Synonyms
- 7-Hydroxy-4-methylcoumarin4-MUBeta-Methylumbelliferone
Fluorescent Indicators
Due to its significant fluorescence, particularly in alkaline environments, 4-Methylumbelliferone serves as a sensitive indicator in various chemical and biochemical analyses. Its emission properties are often exploited for detection purposes.
Biochemical Assays
As a luminescent compound, it is employed in the development and execution of biochemical assays. It acts as a substrate or tag, enabling the detection and quantification of enzymatic activity.
Organic Synthesis Intermediate
4-Methylumbelliferone functions as a versatile building block in organic synthesis. Its heterocyclic coumarin structure allows for further chemical modifications to create more complex molecules.
Fluorescent Probes
The compound's inherent fluorescence, with excitation at 365 nm and emission around 445 nm in methanol, makes it suitable for use as a fluorescent probe in research settings to monitor specific chemical or biological processes.
| Molecular weight | 176.17 |
|---|---|
| Empirical formula | C10H8O3 |
| Assay | ≥98.0% (HPLC) |
| Colour | off-white to yellow |
| Application | Highly fluorescent in alkaline solution. |
| Melting point | 185-190 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 365 nm; λem 445 nm in methanol |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methylumbelliferone used for?
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4-Methylumbelliferone is primarily used as a fluorescent indicator, in biochemical assays, as an intermediate in organic synthesis, and as a fluorescent probe due to its strong luminescent properties, especially in alkaline solutions.
What are the CAS number and molecular formula for 4-Methylumbelliferone?
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The CAS number for 4-Methylumbelliferone is 90-33-5, and its molecular formula is C10H8O3.
What grade and purity does Tech Serve Solutions supply for 4-Methylumbelliferone?
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Tech Serve Solutions supplies 4-Methylumbelliferone with a minimum assay of 98.0% (HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the primary hazards associated with 4-Methylumbelliferone?
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4-Methylumbelliferone is classified as a warning substance. It can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used when handling.
How is 4-Methylumbelliferone packed and shipped?
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4-Methylumbelliferone is carefully packed according to industry standards for chemical reagents and intermediates. TSS exports globally, ensuring compliance with all relevant shipping regulations.
How can I request a quote or sample of 4-Methylumbelliferone?
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To request a quote or a sample of 4-Methylumbelliferone, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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