4-Methylthiophene-2-boronic acid pinacol ester
4-Methylthiophene-2-boronic acid pinacol ester (CAS: 635305-48-5; Formula: C11H17BO2S; MW: 224.13) is a valuable organoboron compound. It functions as a key building block in organic synthesis, particularly in cross-coupling reactions. This heteroaryl boronate ester is supplied by TSS for research and development purposes, enabling the construction of complex molecules.
- IUPAC
- 2-(4-Methyl-2-thienyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane,4-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene,4-Methyl-2-thienylboronic acid pinacol ester
- Synonyms
- 2-(4-Methyl-2-thienyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane4-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene4-Methyl-2-thienylboronic acid pinacol ester
Suzuki-Miyaura Cross-Coupling Reactions
Utilised as a coupling partner in Suzuki-Miyaura reactions to introduce the 4-methyl-2-thienyl moiety into organic molecules. This is crucial for the synthesis of various pharmaceuticals and advanced materials.
Medicinal Chemistry
Serves as an intermediate in the synthesis of biologically active compounds. The thiophene ring system is a common feature in many drug candidates, making this a useful reagent for drug discovery.
Materials Science
Incorporated into the synthesis of novel organic electronic materials, such as conjugated polymers and small molecules for organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
Heterocyclic Chemistry
A versatile reagent for constructing substituted thiophene derivatives, which are important scaffolds in various fields of chemistry.
| Molecular weight | 224.13 |
|---|---|
| Empirical formula | C11H17BO2S |
| Assay | 97% |
| Melting point | 26-31 °C |
Hazard statements
- H413May cause long-lasting harmful effects to aquatic life
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methylthiophene-2-boronic acid pinacol ester used for?
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4-Methylthiophene-2-boronic acid pinacol ester is primarily used as a building block in organic synthesis, especially in Suzuki-Miyaura cross-coupling reactions for creating complex organic molecules, including pharmaceuticals and materials.
What are the CAS number and formula for 4-Methylthiophene-2-boronic acid pinacol ester?
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The CAS number is 635305-48-5 and the empirical formula is C11H17BO2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methylthiophene-2-boronic acid pinacol ester with an assay of 97%. TSS does not represent this product as USP, BP, EP, or any pharmacopoeia grade.
What are the safety and handling considerations for this compound?
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This compound may cause long lasting harmful effects to aquatic life (H413). Appropriate personal protective equipment including eyeshields, gloves, and a suitable respirator should be used during handling.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions professionally packs and exports fine chemicals globally, adhering to all relevant shipping and customs regulations to ensure safe and compliant delivery.
How can I request a sample or quote for 4-Methylthiophene-2-boronic acid pinacol ester?
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You can request a sample or obtain a quote by contacting our sales team via the website or by directly emailing our customer service department.
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