4-Methylthiazole
4-Methylthiazole (CAS: 693-95-8, C4H5NS) is a heterocyclic organic compound with a molecular weight of 99.15 g/mol. This chemical is primarily utilised as a building block in various chemical synthesis processes, particularly within heterocyclic chemistry. It serves as a key intermediate in the preparation of more complex molecules and has found application in the development of functional mimics for enzyme-dependent biological processes.
Synthesis of Catalytic Dendrophanes
4-Methylthiazole has been employed in the synthesis of catalytic dendrophanes. These structures act as functional mimics for thiamine-diphosphate-dependent enzymes, such as pyruvate oxidase.
Preparation of Thiazolium Salts
This compound is used in the small-scale preparation of specific thiazolium salts, for example, 3-butyl-4-methylthiazolium bromide.
Heterocyclic Building Block
As a versatile heterocyclic building block, 4-Methylthiazole is integral to the construction of novel organic compounds within research and development settings.
| Molecular weight | 99.15 |
|---|---|
| Empirical formula | C4H5NS |
| Assay | 99% |
| Boiling point | 133-134 °C(lit.) |
| Density | 1.09 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.524(lit.) |
| Application | 4-Methylthiazole was used in the synthesis of catalytic dendrophanes, as functional mimics of the thiamine-diphosphate-dependent enzyme pyruvate oxidase1. It was used in small scale preparation of 3-butyl-4-methylthiazolium bromide2. |
Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 32 °C / 89.6 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-22-37/38-41 |
| Safety statements (S) | 16-26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methylthiazole used for?
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4-Methylthiazole is used as a building block in chemical synthesis, particularly in the preparation of catalytic dendrophanes and thiazolium salts.
What is the CAS number and formula for 4-Methylthiazole?
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The CAS number for 4-Methylthiazole is 693-95-8, and its empirical formula is C4H5NS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methylthiazole with an assay of 99%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety hazards associated with 4-Methylthiazole?
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4-Methylthiazole is a flammable liquid and vapour (H226). It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment.
How is 4-Methylthiazole shipped?
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4-Methylthiazole is shipped as a UN 1993, Class 3, Packing Group III hazardous material.
How can I request a quote or sample?
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To request a quote or sample of 4-Methylthiazole, please contact our sales department through the website or by phone.
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