4-Methylsalicylic acid
4-Methylsalicylic acid (CAS: 50-85-1), with the molecular formula C8H8O3 and a molar mass of 152.15 g/mol, is a substituted aromatic carboxylic acid. It serves as a valuable building block in organic synthesis and chemical research. Its chemical structure, featuring both a hydroxyl and a carboxyl group on a toluene ring, lends itself to various derivatizations. This compound is primarily utilised in laboratory settings for research and development purposes.
- IUPAC
- 2-Hydroxy-4-methylbenzoic acid,m-Cresotic acid
- Synonyms
- 2-Hydroxy-4-methylbenzoic acidm-Cresotic acid

Biochemical Research
4-Methylsalicylic acid has been employed in biochemical studies to investigate enzyme activity. Specifically, it was used to inhibit medium chain acyl-CoA synthetase, aiding in the understanding of metabolic pathways.
Organic Synthesis Intermediate
As a functionalised aromatic compound, 4-Methylsalicylic acid is a useful intermediate for the synthesis of more complex organic molecules. Its reactive groups allow for diverse chemical transformations in multi-step synthetic routes.
Material Science
Derivatives of 4-Methylsalicylic acid may find applications in material science, contributing to the development of novel polymers or functional materials due to its aromatic and acidic functionalities.
| Molecular weight | 152.15 |
|---|---|
| Linear formula | CH3C6H3(OH)CO2H |
| Assay | 99% |
| Application | 4-Methylsalicylic acid was used to inhibit the medium chain acyl-CoA synthetase1. |
| Melting point | 173-177 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methylsalicylic acid used for?
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4-Methylsalicylic acid is used as a building block in organic synthesis and in biochemical research, for example, to inhibit medium chain acyl-CoA synthetase.
What is the CAS number and formula for 4-Methylsalicylic acid?
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The CAS number for 4-Methylsalicylic acid is 50-85-1, and its molecular formula is C8H8O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methylsalicylic acid with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should 4-Methylsalicylic acid be handled safely?
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4-Methylsalicylic acid is classified with GHS07 symbol and a 'Warning' signal word. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyecups, and gloves, should be used. Handle in a well-ventilated area, avoiding dust formation and inhalation.
Is 4-Methylsalicylic acid a controlled substance?
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Based on the provided data, 4-Methylsalicylic acid is not indicated as a controlled substance.
How can I obtain a quote or sample for 4-Methylsalicylic acid?
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To request a quote or sample of 4-Methylsalicylic acid, please contact the Tech Serve Solutions sales team via our website or direct contact details.
How is 4-Methylsalicylic acid packaged and exported?
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4-Methylsalicylic acid is carefully packaged to maintain its integrity during transit and is available for global export by Tech Serve Solutions.
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