5-Hydroxyflavone
5-Hydroxyflavone (CAS 491-78-1; C15H10O3) is a bioactive flavone derivative supplied by Tech Serve Solutions. With a molecular weight of 238.24 g/mol, this compound serves as a valuable building block and reactant in chemical synthesis. Its applications span the creation of novel bioactive molecules, investigation of metal complexes for antioxidant and insulin-mimetic properties, and studies involving excited-state intramolecular proton transfer.
- IUPAC
- 5-Hydroxy-2-phenylchromone,NSC 26745,Primuletin
- Synonyms
- 5-Hydroxy-2-phenylchromonePrimuletin

Synthesis of Bioactive Copper(II) Complexes
5-Hydroxyflavone acts as a reactant in condensation reactions for the synthesis of copper(II) complexes. These complexes are explored for their potential as bioactive molecules targeting antioxidants.
Investigating Insulin-Mimetic Agents
The compound is employed in thermal behaviour studies of vanadyl complexes with flavone derivatives. These studies aim to understand their potential as insulin-mimetic agents.
O-Methylation Reactions
5-Hydroxyflavone can undergo O-methylation reactions, for example, using di-methyl carbonate as a methylating agent in chemical synthesis.
Photophysical Studies
This compound is used in density functional theory (DFT) studies to investigate fundamental photophysical processes, specifically excited-state intramolecular proton transfer.
| Molecular weight | 238.24 |
|---|---|
| Empirical formula | C15H10O3 |
| Assay | ≥97% |
| Application | Reactant involved in:• Condensation reactions for synthesis of copper(II) complexes as bioactive molecules to combat antioxidants1• Thermal behavior studies of vanadyl complexes with flavone derivatives in terms of insulin-mimetic agents2• O-methylation with di-Me carbonate3• DFT studies on excited-state intramolecular proton transfer4 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | rat ... Gabra2(29706) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Hydroxyflavone used for?
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5-Hydroxyflavone is used as a reactant in condensation reactions for synthesizing copper(II) complexes with antioxidant potential, in thermal studies of vanadyl complexes for insulin-mimetic properties, for O-methylation, and in DFT studies of excited-state intramolecular proton transfer.
What are the CAS number and formula for 5-Hydroxyflavone?
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The CAS number is 491-78-1 and the empirical formula is C15H10O3.
What grade and purity does Tech Serve Solutions supply for 5-Hydroxyflavone?
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Tech Serve Solutions supplies 5-Hydroxyflavone with an assay of ≥97%. This is suitable for research and chemical synthesis; TSS does not represent it as USP, BP, or EP grade.
What safety precautions should be taken when handling 5-Hydroxyflavone?
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When handling 5-Hydroxyflavone, it is essential to wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is also recommended. The WGK is 3.
How is 5-Hydroxyflavone packed, shipped, and exported?
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Tech Serve Solutions professionally packs, handles, and exports 5-Hydroxyflavone in compliance with all relevant international shipping regulations for chemical compounds.
How can I request a sample or quote for 5-Hydroxyflavone?
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To request a sample or a quote for 5-Hydroxyflavone, please contact our sales team via the website or directly by email or phone.
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