5-Hydroxy-L-tryptophan
5-Hydroxy-L-tryptophan (CAS 4350-09-8), with the molecular formula C11H12N2O3, is a naturally occurring amino acid. It functions as a biochemical intermediate in the biosynthesis of the neurotransmitter serotonin and the hormone melatonin. This compound is primarily utilised in biochemical research, cell biology studies, and as a precursor in chemical synthesis for various tryptophan derivatives.

Biochemical Research
Serves as a vital intermediate in the metabolic pathways of serotonin and melatonin, making it a key compound for neurochemical research and studies on neurotransmitter function.
Cell Biology Studies
Used in cell culture and biological assays to investigate cellular processes related to amino acid metabolism and protein synthesis, particularly within research settings.
Chemical Synthesis
Acts as a building block for the synthesis of various tryptophan derivatives and related compounds, valuable in medicinal chemistry and the development of novel molecules.
Nutrition Research
Investigated for its role in nutritional science and its potential influence on physiological processes, contributing to a deeper understanding of dietary components.
| Molecular weight | 220.22 |
|---|---|
| Empirical formula | C11H12N2O3 |
| Assay | ≥99.0% (calc. based on dry substance, NT) |
| Density | 0.902 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4850(lit.) |
| Optical activity | [α]20/D −33±2°, c = 1% in H2O |
| Loss on drying | ≤2% loss on drying |
| Melting point | 270 °C (dec.)(lit.)~275 °C (dec.) |
| Storage temperature | 2-8°C |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
| Ignition residue | ≤0.05% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Hydroxy-L-tryptophan used for?
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5-Hydroxy-L-tryptophan is used in biochemical research, cell biology studies, chemical synthesis of tryptophan derivatives, and nutrition research due to its role as an intermediate in serotonin and melatonin biosynthesis.
What are the CAS number and formula for 5-Hydroxy-L-tryptophan?
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The CAS number for 5-Hydroxy-L-tryptophan is 4350-09-8, and its molecular formula is C11H12N2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Hydroxy-L-tryptophan with an assay of ≥99.0% (calc. based on dry substance, NT). We do not represent this product as USP, BP, or EP grade.
How should 5-Hydroxy-L-tryptophan be handled and stored?
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Handle 5-Hydroxy-L-tryptophan with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, face shield, and gloves. Store at 2-8°C. It is classified as Danger with hazard statements H301, H315, H319, and H335.
How is 5-Hydroxy-L-tryptophan packed and exported?
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5-Hydroxy-L-tryptophan is packed according to industry standards for chemical export and is shipped globally by Tech Serve Solutions.
How can I request a sample or quote for 5-Hydroxy-L-tryptophan?
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To request a sample or quote for 5-Hydroxy-L-tryptophan, please contact the Tech Serve Solutions sales team via our website or direct contact details.
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