5-Chloro-3-((trimethylsilyl)ethynyl)pyridin-2-amine
5-Chloro-3-((trimethylsilyl)ethynyl)pyridin-2-amine (CAS: 866318-90-3) is a halogenated pyridine derivative with the molecular formula C10H13ClN2Si and a molecular weight of 224.76 g/mol. This compound serves as a valuable building block in organic synthesis, particularly within the fields of medicinal chemistry and materials science. Its unique structure, featuring both a silylated alkyne and a chlorinated pyridine core, enables diverse chemical transformations for creating complex molecular architectures.

Organic Synthesis Building Block
Utilised in the construction of more complex organic molecules, especially within pharmaceutical and agrochemical research and development. The compound's functional groups allow for versatile coupling and derivatisation reactions.
Medicinal Chemistry Research
Incorporated into the synthesis of novel drug candidates due to the presence of the pyridine scaffold and reactive sites, which are common motifs in biologically active compounds.
Materials Science Applications
Potentially employed in the development of new functional materials, such as organic electronic components or polymers, where its specific electronic and structural properties can be leveraged.
| Molecular weight | 224.76 |
|---|---|
| Empirical formula | C10H13ClN2Si |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloro-3-((trimethylsilyl)ethynyl)pyridin-2-amine used for?
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This compound is primarily used as a building block in organic synthesis, including applications in medicinal chemistry research and materials science.
What are the CAS number and molecular formula?
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The CAS number is 866318-90-3, and the molecular formula is C10H13ClN2Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a research-grade material. We do not represent it as USP, BP, or EP grade, and purity is detailed on the Certificate of Analysis.
What are the safety and handling considerations?
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This chemical may cause skin irritation and serious eye irritation. Handle with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for comprehensive safety information.
How is this chemical packed and exported?
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We offer various packing sizes suitable for laboratory and bulk quantities, adhering to international shipping regulations for chemical export.
How can I request a sample or quote?
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Please contact our sales team via the website or direct email to request a sample or obtain a quotation for 5-Chloro-3-((trimethylsilyl)ethynyl)pyridin-2-amine.
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