5-Chloro-3-hydroxypyridine
5-Chloro-3-hydroxypyridine (CAS: 74115-12-1, C5H4ClNO) is a halogenated heterocyclic building block with a molecular weight of 129.54 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly in the development of novel chemical entities. Its structure makes it suitable for further functionalisation in complex molecule construction. Tech Serve Solutions supplies this pyridine derivative with a high purity assay.
- IUPAC
- 5-Chloro-3-pyridinol

Organic Synthesis Intermediate
5-Chloro-3-hydroxypyridine is employed as a key building block in multi-step synthetic routes. It is utilised for the introduction of the chloropyridinol moiety into target molecules, facilitating the creation of complex heterocyclic structures.
Pharmaceutical Research
This compound finds application in the synthesis of potential pharmaceutical agents. Its unique structure allows for exploration in medicinal chemistry programmes aiming to develop new therapeutic candidates.
Materials Science
As a functionalised heterocycle, 5-Chloro-3-hydroxypyridine can be investigated for its incorporation into advanced materials where specific electronic or structural properties are desired.
| Molecular weight | 129.54 |
|---|---|
| Empirical formula | C5H4ClNO |
| Assay | 99% |
| Application | 5-Chloro-3-hydroxypyridine was used in the preparation of 4-(5-chloropyridin-3-yloxy)isoquinoline1. |
| Melting point | 160-162 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloro-3-hydroxypyridine used for?
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5-Chloro-3-hydroxypyridine (CAS: 74115-12-1) is primarily used as a building block in organic synthesis, including the preparation of pharmaceutical intermediates and potentially in materials science research.
What are the CAS number and chemical formula for 5-Chloro-3-hydroxypyridine?
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The CAS number for 5-Chloro-3-hydroxypyridine is 74115-12-1. Its empirical formula is C5H4ClNO, with a molecular weight of 129.54 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Chloro-3-hydroxypyridine with an assay of 99%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should 5-Chloro-3-hydroxypyridine be handled?
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5-Chloro-3-hydroxypyridine is classified as an irritant. Handle with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. Refer to the Safety Data Sheet for detailed handling instructions.
Is 5-Chloro-3-hydroxypyridine a controlled substance?
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Based on the provided data, 5-Chloro-3-hydroxypyridine is not indicated as a controlled substance.
How is 5-Chloro-3-hydroxypyridine packed and shipped?
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Tech Serve Solutions exports fine chemicals globally, ensuring appropriate packaging for safe transport. Please contact us for specific details regarding packing and shipping for your region.
How can I request a sample or quote for 5-Chloro-3-hydroxypyridine?
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To request a sample or a quotation for 5-Chloro-3-hydroxypyridine, please contact our sales department via the website or direct email, specifying your requirements and delivery location.
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