IB-MECA
IB-MECA (CAS: 152918-18-8), with the empirical formula C18H19IN6O4 and a molecular weight of 510.29 g/mol, is a white solid compound. It functions as an agonist for Adenosine/P2 Nucleotide Receptors, primarily within the purinergic signalling pathway. This makes IB-MECA a valuable tool in cell biology and neuroscience research, particularly for investigating cell signaling and neurotransmission.
- IUPAC
- 1-Deoxy-1-[6-[((3-Iodophenyl)methyl)amino]-9H-purin-9-yl]-N-methyl-β-D-ribofuranuronamide,N6-(3-Iodobenzyl)adenosine-5′-N-methyluronamide
- Synonyms
- 1-Deoxy-1-[6-[((3-Iodophenyl)methyl)amino]-9H-purin-9-yl]-N-methyl-β-D-ribofuranuronamide,N6-(3-Iodobenzyl)adenosine-5′-N-methyluronamide

Adenosine Receptor Research
IB-MECA acts as an agonist for various adenosine receptors, including ADORA1, ADORA2A, ADORA2B, and ADORA3 in humans, and their counterparts in rats. It is used to study the physiological roles of these receptors in cell signaling and neurotransmission.
Neuroscience Investigations
As a potent agonist for purinergic receptors, IB-MECA is employed in neuroscience research to probe the mechanisms of neurotransmission and neuromodulation. Its selectivity allows for detailed study of specific purinergic pathways.
Cell Signaling Studies
This compound serves as a bioactive small molecule for investigating intracellular and intercellular communication pathways. Researchers utilise IB-MECA to understand how purinergic signaling impacts cellular functions.
| Molecular weight | 510.29 |
|---|---|
| Empirical formula | C18H19IN6O4 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | ethanol: >10 mg/mL (hot)DMSO: >5 mg/mLH2O: insolubleaqueous acid: insolubleaqueous base: insoluble |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)rat ... Adora1(29290), Adora2a(25369), Adora3(25370) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is IB-MECA used for?
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IB-MECA is primarily used as an agonist for adenosine/P2 nucleotide receptors in research settings, particularly within cell biology and neuroscience for studying cell signaling and neurotransmission.
What is the CAS number and chemical formula for IB-MECA?
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The CAS number for IB-MECA is 152918-18-8, and its empirical formula is C18H19IN6O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies IB-MECA with a purity of ≥98% by HPLC. We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should IB-MECA be handled and stored?
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Handle IB-MECA with appropriate personal protective equipment, including eyeshields and gloves, and use a type N95 (US) or type P1 (EN143) respirator filter if necessary. Store the compound at 2-8°C.
Is IB-MECA a hazardous substance?
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IB-MECA is classified under WGK Germany 3. Appropriate safety precautions as detailed in the safety information section must be followed during handling and storage.
How is IB-MECA packed and shipped?
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IB-MECA is carefully packed according to international shipping regulations for research chemicals and exported globally by Tech Serve Solutions.
How can I request a quote or sample for IB-MECA?
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To request a quote or sample of IB-MECA, please contact our sales team through the Tech Serve Solutions website or by phone.
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