I-AB-MECA

CAS 152918-27-9C18H20IN7O4Cell Biology

I-AB-MECA (CAS 152918-27-9), with the molecular formula C18H20IN7O4 and a molecular weight of 525.30 g/mol, is an iodinated adenosine derivative. This off-white solid is primarily utilised as a research chemical in cell biology and neuroscience. Its specific applications revolve around the study of adenosine receptors and neurotransmission, making it a valuable tool for investigating cellular signalling pathways.

IUPAC: 1-[6-[[(4-Amino-3-iodophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-β-D-ribofuranuronamide,3-Iodo-4-aminobenzyl-5′-N-methylcarboxamidoadenosine,N6-(4-Amino-3-iodobenzyl)-5′-N-methylcarbamoyladenosine
Synonyms: 1-[6-[[(4-Amino-3-iodophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-β-D-ribofuranuronamide3-Iodo-4-aminobenzyl-5′-N-methylcarboxamidoadenosineN6-(4-Amino-3-iodobenzyl)-5′-N-methylcarbamoyladenosine

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I-AB-MECA (C18H20IN7O4) — chemical structure, CAS 152918-27-9; Life Science, fine chemical supplied by Tech Serve Solutions

A-AMBioactive Small MoleculesCell BiologyNeuroscienceNeurotransmissionNeurotransmittersOthers More...

01 /Applications

Adenosine Receptor Research

I-AB-MECA serves as a pharmacological tool to investigate the function and subtypes of adenosine receptors (P2 Nucleotide Receptors). Researchers use it to study purinergic signalling pathways in various biological systems.

Neuroscience and Neurotransmission Studies

This compound is employed in neuroscience research to explore mechanisms of neurotransmission. It can be used to study the role of adenosine and its analogues in modulating neuronal activity and signalling.

Cell Biology Investigations

As a bioactive small molecule, I-AB-MECA aids in cellular biology research by allowing scientists to probe cellular processes, receptor interactions, and intracellular signalling cascades.

02 /Properties

Molecular weight	525.30
Empirical formula	C18H20IN7O4
Form	solid
Colour	off-white
Solubility	45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble0.2 mg/mLDMSO: soluble10 mg/mL0.1 M NaOH: soluble2 mg/mL0.1 M HCl: soluble7 mg/mLH2O: insoluble
Storage temperature	−20°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

152918-27-9

MDL number

MFCD00671784

05 /Additional specifications

Gene Information	human ... ADORA3(140)rat ... Adora1(29290), Adora2a(25369), Adora3(25370)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is I-AB-MECA used for?

I-AB-MECA is primarily used as a research chemical in cell biology, neuroscience, and for studying adenosine receptors and neurotransmission.

What is the CAS number and chemical formula for I-AB-MECA?

The CAS number is 152918-27-9 and the chemical formula is C18H20IN7O4.

What grade and purity does Tech Serve Solutions supply for I-AB-MECA?

Tech Serve Solutions supplies I-AB-MECA for research purposes. The specific assay and purity are available upon request or via the product's certificate of analysis. We do not represent this product as USP, BP, or EP grade.

What are the safety considerations when handling I-AB-MECA?

Handling I-AB-MECA requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound has a WGK rating of 3 in Germany, indicating a high hazard to water.

How is I-AB-MECA typically stored and shipped?

I-AB-MECA should be stored at -20°C. As a global supplier, Tech Serve Solutions ensures appropriate packaging and shipping procedures for chemical export worldwide.