ICRF-193
ICRF-193 (CAS 21416-88-6), with the molecular formula C12H18N4O4 and a molecular weight of 282.30 g/mol, is a chemical compound primarily utilised in cellular biology research. It functions as an inhibitor of RNA-protein translation, making it valuable for studying gene regulation and expression. Its specific applications are found within cell signaling and neuroscience research, contributing to a deeper understanding of cellular mechanisms.
- IUPAC
- meso-4,4′-(3,2-Butanediyl)-bis(2,6-piperazinedione)
Gene Regulation Studies
ICRF-193 is employed to investigate the intricate processes of gene regulation and expression by inhibiting RNA-protein translation. This allows researchers to dissect specific pathways and understand how gene activity is controlled at the molecular level.
Cell Signaling Research
In cell signaling pathways, ICRF-193 can be used as a tool to modulate protein synthesis. This helps in elucidating the roles of specific proteins and their interactions in various cellular communication networks.
Neuroscience Investigations
Within neuroscience, this compound aids in studying the impact of translation inhibition on neuronal function and development. It can be instrumental in understanding neurological processes and potential therapeutic targets.
RNA-Protein Translation Inhibition
As a specific inhibitor of RNA-protein translation, ICRF-193 is directly used to block the synthesis of proteins from mRNA templates. This is crucial for experiments requiring precise control over protein production.
| Molecular weight | 282.30 |
|---|---|
| Empirical formula | C12H18N4O4 |
| Assay | ≥95% |
| Solubility | DMSO: soluble4 mg/mL |
| Storage temperature | −20°C |
Hazard statements
- H301Toxic if swallowed
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-43 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is ICRF-193 used for?
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ICRF-193 is used in research for studying gene regulation and expression, cell signaling, neuroscience, and specifically as an inhibitor of RNA-protein translation.
What are the CAS number and formula for ICRF-193?
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The CAS number for ICRF-193 is 21416-88-6, and its molecular formula is C12H18N4O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies ICRF-193 with an assay of ≥95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should ICRF-193 be handled safely?
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ICRF-193 is classified as a Danger. It is toxic if swallowed (H301) and may cause an allergic skin reaction (H317). Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, faceshields, and gloves, must be worn. Always handle in a well-ventilated area.
How is ICRF-193 packed, shipped, and exported?
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ICRF-193 is stored at -20°C. It is shipped as UN 2811, Class 6.1, Packing Group III. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring compliant packaging and international shipment.
How can I request a sample or quote for ICRF-193?
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To request a sample or a quote for ICRF-193, please contact our sales team through the website or by phone, providing your details and the quantity required.
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