IM-12

CAS 1129669-05-1C22H20FN3O2Cell Biology

IM-12 (CAS: 1129669-05-1) is a bioactive small molecule with the chemical formula C22H20FN3O2 and a molecular weight of 377.41 g/mol. This yellow-orange powder is primarily utilised in biochemical research, particularly within cell biology and cell signalling studies. It acts as an inhibitor for Glycogen Synthase Kinase 3 (GSK3), making it a valuable tool for investigating kinase/phosphatase biology and serine/threonine kinase pathways.

IUPAC: 3-(4-Fluorophenylethylamino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

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IM-12 (C22H20FN3O2) — chemical structure, CAS 1129669-05-1; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesCell BiologyKinase/Phosphatase Biology

01 /Applications

Glycogen Synthase Kinase 3 (GSK3) Inhibition

IM-12 is a potent inhibitor of GSK3, crucial for research into cellular processes regulated by this kinase. It aids in understanding GSK3's role in various signalling pathways.

Cell Signalling and Neuroscience Research

Its ability to modulate GSK3 activity makes IM-12 a relevant tool for studying cell signalling cascades, particularly in neuroscience applications where GSK3 is implicated in neuronal function and disease.

Kinase/Phosphatase Pathway Analysis

Researchers employ IM-12 to investigate the complex interplay within kinase and phosphatase biological systems. It helps elucidate the downstream effects of GSK3 inhibition.

Serine/Threonine Kinase Biology Studies

As a selective inhibitor within the serine/threonine kinase family, IM-12 is used to probe specific biochemical pathways and validate targets in drug discovery research.

02 /Properties

Molecular weight	377.41
Empirical formula	C22H20FN3O2
Assay	≥98% (HPLC)
Form	powder
Colour	yellow-orange
Solubility	DMSO: ≥9 mg/mL
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed

Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

1129669-05-1

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is IM-12 used for?

IM-12 is primarily used in biochemical research as a Glycogen Synthase Kinase 3 (GSK3) inhibitor. It is valuable for studying cell signalling, kinase/phosphatase biology, and neuroscience.

What are the CAS number and chemical formula for IM-12?

The CAS number for IM-12 is 1129669-05-1, and its chemical formula is C22H20FN3O2.

What grade and purity does Tech Serve Solutions supply for IM-12?

Tech Serve Solutions supplies IM-12 with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade; it is intended for research and laboratory use.

What are the safety and handling requirements for IM-12?

IM-12 is classified with the GHS07 symbol and a Warning signal word. It carries the hazard statement H302 (Harmful if swallowed). Handle with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for detailed handling instructions.

How is IM-12 shipped and exported by TSS?

IM-12 is stored at 2-8°C and can be securely packed and exported globally by Tech Serve Solutions to meet research and laboratory needs.

How can I request a quote or sample of IM-12?

To request a quote or a sample of IM-12, please contact our sales team through the Tech Serve Solutions website or by direct inquiry, providing your contact details and intended use.