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6-O-Methylguanine

CAS 20535-83-5C6H7N5OChemical Synthesis

6-O-Methylguanine (CAS: 20535-83-5) is a purine derivative with the molecular formula C6H7N5O. This bioactive small molecule serves as a crucial building block in chemical synthesis and cell biology research. Its applications span the investigation of DNA repair mechanisms and as a reagent in the development of novel heterocyclic compounds. TSS provides high-quality 6-O-Methylguanine for demanding scientific and industrial applications.

IUPAC
2-Amino-6-methoxypurine,6-Methoxyguanine
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6-O-Methylguanine (C6H7N5O) — chemical structure, CAS 20535-83-5; Chemistry, fine chemical supplied by Tech Serve Solutions
Bioactive Small MoleculesBuilding BlocksCell BiologyChemical SynthesisHeterocyclic Building BlocksPurines More...
01 /Applications

DNA Repair Research

6-O-Methylguanine is a key intermediate in understanding DNA alkylation and repair pathways, particularly the action of O6-alkylguanine-DNA alkyltransferase (MGMT). Researchers utilise it to study genotoxicity and mutagenicity.

Chemical Synthesis

As a heterocyclic building block, it is employed in the synthesis of complex organic molecules and potential pharmaceutical candidates. Its purine structure makes it valuable for creating modified nucleosides and related compounds.

Cell Biology Studies

This compound aids in investigations related to cellular processes influenced by DNA damage and repair, contributing to a deeper understanding of cell cycle regulation and apoptosis.

02 /Properties
Molecular weight165.15
Empirical formulaC6H7N5O
Assay97%
Melting point>300 °C(lit.)
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
20535-83-5
MDL number
MFCD00133009
PubChem substance
24862349
Beilstein registry
645384
05 /Additional specifications
Gene Informationhuman ... CDK2(1017), MGMT(4255)
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is 6-O-Methylguanine used for?

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6-O-Methylguanine is used in DNA repair research, chemical synthesis as a building block, and in cell biology studies.

What are the CAS number and formula for 6-O-Methylguanine?

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The CAS number is 20535-83-5, and the empirical formula is C6H7N5O.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 6-O-Methylguanine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.

What are the safety and handling requirements for 6-O-Methylguanine?

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Handling 6-O-Methylguanine requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK Germany 3.

How is 6-O-Methylguanine packed, shipped, and exported?

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Tech Serve Solutions expertly packs, ships, and exports fine chemicals globally, adhering to all relevant regulations for safe and timely delivery.

How can I request a sample or quote for 6-O-Methylguanine?

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To request a sample or quote for 6-O-Methylguanine, please contact our sales team via the website or by phone.

Need 6-O-Methylguanine in a specific grade or volume?