4′-Bromo-2,2,2-trifluoroacetophenone
4′-Bromo-2,2,2-trifluoroacetophenone (CAS: 16184-89-7) is a versatile trifluoromethyl ketone with a molecular weight of 253.02. This organic building block, featuring a bromine atom on the phenyl ring, is a valuable intermediate in chemical synthesis. It is particularly useful in the preparation of more complex molecules, including pharmaceuticals and agrochemicals, owing to its reactive carbonyl group and aryl bromide functionality. Tech Serve Solutions supplies this compound with an assay of ≥98%.
- IUPAC
- 4-Bromo-α,α,α-trifluoroacetophenone
- Synonyms
- 16184-89-7BrC6H4COCF34-Bromo-α,α,α-trifluoroacetophenone
Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs) and drug discovery programmes. Its structure allows for further functionalisation in medicinal chemistry.
Agrochemical Synthesis
Serves as a building block for novel pesticides, herbicides, and fungicides. The trifluoromethyl and bromo-phenyl groups can impart desirable properties to agrochemical compounds.
Organic Synthesis Reagent
A useful reagent in organic chemistry laboratories for introducing the 4-bromophenyl trifluoromethyl ketone moiety into various organic structures.
Material Science Research
Investigated for potential applications in the development of new materials and polymers where its specific electronic and structural properties may be beneficial.
| Molecular weight | 253.02 |
|---|---|
| Linear formula | BrC6H4COCF3 |
| Assay | ≥98% |
| Boiling point | 95 °C/4 mmHg(lit.) |
| Density | 1.662 g/mL at 25 °C(lit.) |
| Melting point | 26-30 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 96 °C / 204.8 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4′-Bromo-2,2,2-trifluoroacetophenone used for?
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It is primarily used as a building block and intermediate in the synthesis of pharmaceuticals, agrochemicals, and other complex organic molecules, as well as in material science research.
What is the CAS number and formula for 4′-Bromo-2,2,2-trifluoroacetophenone?
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The CAS number is 16184-89-7 and the linear formula is BrC₆H₄COCF₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4′-Bromo-2,2,2-trifluoroacetophenone with a minimum purity of ≥98%. This is a technical/research grade; TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling precautions for this chemical?
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This compound is a Warning substance (GHS07) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. Handle in a well-ventilated area.
How is 4′-Bromo-2,2,2-trifluoroacetophenone packed, shipped, and exported?
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Tech Serve Solutions carefully packs and labels all chemicals according to international regulations for safe handling, storage, and transportation. We are experienced global exporters of fine chemicals.
How can I request a sample or a quote?
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Please use the contact form on our website or call us directly to request a sample or a quotation for 4′-Bromo-2,2,2-trifluoroacetophenone.
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