5-Bromo-2-thiophenylboronic acid MIDA ester
5-Bromo-2-thiophenylboronic acid MIDA ester (CAS 943552-31-6) is a valuable organoboron compound with the empirical formula C9H9BBrNO4S and a molecular weight of 317.95 g/mol. As a stable MIDA boronate derivative, it serves as a versatile building block in organic synthesis, particularly for cross-coupling reactions where boronic acid surrogates are advantageous. Its primary application lies in facilitating complex chemical transformations.
- IUPAC
- 2-(5-Bromothiophen-2-yl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione,5-Bromothiophene-2-boronic acid MIDA ester
- Synonyms
- 2-(5-Bromothiophen-2-yl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione5-Bromothiophene-2-boronic acid MIDA ester
Suzuki Cross-Coupling Reactions
This compound acts as a stable boronic acid surrogate in Suzuki cross-coupling reactions, enabling the formation of carbon-carbon bonds under mild conditions. It is particularly useful for challenging coupling partners.
Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of complex organic molecules, including pharmaceuticals and advanced materials. Its structure allows for regioselective functionalisation.
Heteroaryl MIDA Boronate Chemistry
As a heteroaryl MIDA boronate, it participates in reactions that introduce thiophene moieties into molecular frameworks, important in medicinal chemistry and material science.
| Molecular weight | 317.95 |
|---|---|
| Empirical formula | C9H9BBrNO4S |
| Assay | 95% |
| Application | MIDA boronates as stable boronic acid surrogates for classically challenging cross-couplings1,2Suzuki Cross-Coupling with MIDA Boronates |
| Melting point | 151-156 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Bromo-2-thiophenylboronic acid MIDA ester used for?
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5-Bromo-2-thiophenylboronic acid MIDA ester is primarily used as a building block in organic synthesis, particularly for Suzuki cross-coupling reactions and other carbon-carbon bond-forming transformations. It serves as a stable surrogate for boronic acids in complex synthetic routes.
What are the CAS number and formula for 5-Bromo-2-thiophenylboronic acid MIDA ester?
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The CAS number is 943552-31-6. The empirical formula is C9H9BBrNO4S, and the molecular weight is 317.95 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Bromo-2-thiophenylboronic acid MIDA ester with an assay of 95%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for this chemical?
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This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It has a WGK Germany rating of 3, indicating it is a substance hazardous to water. Handle with care in a well-ventilated area.
How is 5-Bromo-2-thiophenylboronic acid MIDA ester packed, shipped, and exported?
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Tech Serve Solutions expertly packs, ships, and exports fine chemicals globally, adhering to all necessary regulations for safe and compliant international transit. Specific packaging details can be provided upon request.
How can I request a sample or quote for 5-Bromo-2-thiophenylboronic acid MIDA ester?
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To request a sample or a quotation for 5-Bromo-2-thiophenylboronic acid MIDA ester, please contact our sales team through the website or by phone, providing your contact details and the quantity required.
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