5-Bromo-2-thienylboronic acid
5-Bromo-2-thienylboronic acid (CAS: 162607-17-2) is a heteroaryl boronic acid derivative with the molecular formula C4H4BBrO2S and a molecular weight of 206.85 g/mol. This organometallic reagent serves as a key building block in organic synthesis, particularly in cross-coupling reactions. It is instrumental in constructing complex organic molecules, finding utility in the development of advanced materials and pharmaceutical intermediates.
- IUPAC
- 5-Bromothiophene-2-boronic acid
- Synonyms
- 5-Bromothiophene-2-boronic acid
Suzuki Coupling Reactions
This boronic acid is a valuable reactant in Suzuki coupling reactions, enabling the synthesis of benzotriazole-containing organic sensitizers and <i>meso</i>-polyarylamide-BODIPY hybrids. It facilitates the formation of new carbon-carbon bonds crucial for these complex molecular architectures.
Suzuki-Miyaura Coupling for Ratanhine Synthesis
It is employed in Suzuki-Miyaura coupling reactions specifically for the synthesis of ratanhine. This application highlights its utility in constructing specific alkaloid structures.
Sonogashira Reactions for Ethynylarylboronates
The compound participates in microwave-assisted Sonogashira reactions, leading to the synthesis of ethynylarylboronates. This demonstrates its versatility in forming carbon-carbon triple bonds.
| Molecular weight | 206.85 |
|---|---|
| Empirical formula | C4H4BBrO2S |
| Storage temperature | 2-8°C |
| Application | Reactant involved in:• Suzuki coupling reactions for the synthesis of benzotriazole-containing organic sensitizers1 and meso-Polyarylamide-BODIPY hybrids2• Suzuki-Miyaura coupling for the synthesis of ratanhine3• Microwave-assisted Sonogashira reactions for the synthesis of ethynylarylboronates4 |
| Melting point | 95-100 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Bromo-2-thienylboronic acid used for?
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5-Bromo-2-thienylboronic acid is primarily used as a reactant in various cross-coupling reactions, including Suzuki coupling for the synthesis of organic sensitizers and complex hybrids, Suzuki-Miyaura coupling for alkaloid synthesis, and Sonogashira reactions to produce ethynylarylboronates.
What are the CAS number and formula for 5-Bromo-2-thienylboronic acid?
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The CAS number for 5-Bromo-2-thienylboronic acid is 162607-17-2, and its empirical formula (Hill notation) is C4H4BBrO2S.
What grade and purity does Tech Serve Solutions supply for 5-Bromo-2-thienylboronic acid?
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Tech Serve Solutions supplies 5-Bromo-2-thienylboronic acid typically as a research or technical grade material. The precise assay and grade are available on the product's Certificate of Analysis. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for 5-Bromo-2-thienylboronic acid?
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Handling 5-Bromo-2-thienylboronic acid requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with a WGK of 3 in Germany, indicating a high hazard to water.
How is 5-Bromo-2-thienylboronic acid packed, shipped, and exported?
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Tech Serve Solutions carefully packs and ships 5-Bromo-2-thienylboronic acid according to international regulations for chemical transport. We are experienced global exporters, ensuring compliance and product integrity throughout the shipping process.
How can I request a sample or a quote for 5-Bromo-2-thienylboronic acid?
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To request a sample or a quote for 5-Bromo-2-thienylboronic acid, please contact our sales department through the website or by phone. Our team will assist you with your inquiry.
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