6-Bromo-2H-1,4-benzoxazin-3(4H)-one
6-Bromo-2H-1,4-benzoxazin-3(4H)-one (CAS 24036-52-0) is a heterocyclic organic compound with the molecular formula C8H6BrNO2 and a molecular weight of 228.04 g/mol. As a brominated benzoxazine derivative, it serves as a valuable intermediate and building block in organic synthesis. Its primary application lies in the construction of more complex molecular architectures, notably in the development of pyrimidinyl substituted benzoxazinones and small molecule rennin inhibitors.
- Synonyms
- 6-Bromo-1,4-benzoxazin-3-one6-bromo-4H-benzo[b][1,4]oxazin-3-one
Synthesis of Pyrimidinyl Substituted Benzoxazinones
This compound is a key intermediate for constructing pyrimidinyl substituted benzoxazinone structures. These derivatives are of interest in medicinal chemistry for potential therapeutic applications.
Development of Rennin Inhibitors
6-Bromo-2H-1,4-benzoxazin-3(4H)-one is utilised in the synthesis of small molecule rennin inhibitors. Rennin is an enzyme that plays a role in blood pressure regulation, making its inhibitors relevant for cardiovascular research.
Halogenated Heterocyclic Building Block
The presence of the bromine atom on the benzoxazine core makes it a useful building block for further functionalisation in organic synthesis, particularly for creating diverse halogenated heterocyclic compounds.
| Molecular weight | 228.04 |
|---|---|
| Empirical formula | C8H6BrNO2 |
| Assay | 97% |
| Application | Building block used in the construction of pyrimidinyl substituted benzoxazinones, small molecule rennin inhibitors.1 |
| Melting point | 220-225 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Bromo-2H-1,4-benzoxazin-3(4H)-one used for?
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6-Bromo-2H-1,4-benzoxazin-3(4H)-one is primarily used as a building block in organic synthesis for the construction of pyrimidinyl substituted benzoxazinones and small molecule rennin inhibitors.
What is the CAS number and formula for this compound?
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The CAS number is 24036-52-0, and the molecular formula is C8H6BrNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-Bromo-2H-1,4-benzoxazin-3(4H)-one with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the main safety considerations when handling this chemical?
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This compound is classified with a Warning signal word. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment including a dust mask (N95 type), eyeshields, and gloves should be used. Handle in a well-ventilated area.
How is this chemical typically packed and exported?
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As a specialist global supplier, Tech Serve Solutions ensures that 6-Bromo-2H-1,4-benzoxazin-3(4H)-one is packed and exported in compliance with all relevant international shipping regulations for chemical substances.
How can I request a sample or a quote for 6-Bromo-2H-1,4-benzoxazin-3(4H)-one?
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Please contact our sales team via the website or by phone to request a sample or a quotation for 6-Bromo-2H-1,4-benzoxazin-3(4H)-one.
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