5-Bromo-3-((trimethylsilyl)ethynyl)pyridin-2-amine
5-Bromo-3-((trimethylsilyl)ethynyl)pyridin-2-amine (CAS: 905966-34-9) is a halogenated pyridine derivative with the molecular formula C10H13BrN2Si and a molecular weight of 269.21 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in the construction of complex heterocyclic structures. Its unique combination of a bromo substituent and a silyl-protected ethynyl group on a pyridine core makes it suitable for various cross-coupling reactions and further functionalization in medicinal chemistry and materials science research.

Organic Synthesis Intermediate
This compound is employed as a versatile building block in the synthesis of novel organic molecules. The presence of the bromine atom and the trimethylsilyl-protected alkyne allows for selective functionalization via reactions such as Suzuki, Sonogashira, or Stille couplings.
Medicinal Chemistry
It can be utilised in the development of new pharmaceutical agents. The pyridine core is a common feature in many bioactive compounds, and the specific substitution pattern of this molecule offers opportunities for structure-activity relationship studies.
Materials Science
The compound's structure lends itself to applications in the creation of advanced materials, potentially for electronics or functional polymers, where precise molecular architecture is critical.
| Molecular weight | 269.21 |
|---|---|
| Empirical formula | C10H13BrN2Si |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Bromo-3-((trimethylsilyl)ethynyl)pyridin-2-amine used for?
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5-Bromo-3-((trimethylsilyl)ethynyl)pyridin-2-amine is primarily used as a building block in organic synthesis, with applications in medicinal chemistry and materials science research.
What is the CAS number and formula for 5-Bromo-3-((trimethylsilyl)ethynyl)pyridin-2-amine?
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The CAS number is 905966-34-9 and the empirical formula is C10H13BrN2Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a research-grade chemical. The specific assay or purity is available on the product's Certificate of Analysis. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should 5-Bromo-3-((trimethylsilyl)ethynyl)pyridin-2-amine be handled?
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According to GHS classifications, this compound may cause skin irritation, serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment in a well-ventilated area.
Is this compound shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including this product.
How can I request a sample or quote for this chemical?
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Please contact our sales department via the website or direct email to request a sample or a quotation for this product.
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