N-Trityl-L-serine lactone
N-Trityl-L-serine lactone (CAS 88109-06-2) is a chiral building block with the molecular formula C22H19NO2. This compound serves as a valuable intermediate in asymmetric synthesis and peptide chemistry. Its trityl protecting group offers stability during various synthetic transformations, making it suitable for the construction of complex molecules and the development of novel chemical entities in research and development settings.
- IUPAC
- (S)-3-(Tritylamino)-2-oxetanone
Chiral Synthesis Intermediate
N-Trityl-L-serine lactone functions as a key chiral building block in the synthesis of enantiomerically pure compounds. Its defined stereochemistry is crucial for creating stereospecific molecules used in pharmaceuticals and advanced materials.
Peptide Chemistry
This compound is employed in peptide synthesis, where the trityl group protects the amino terminus. The lactone structure allows for specific reactions, facilitating the controlled assembly of peptide chains.
Heterocyclic Compound Synthesis
The oxetane ring within N-Trityl-L-serine lactone makes it a useful precursor for synthesizing various heterocyclic compounds, including other strained ring systems or modified amino acid derivatives.
Asymmetric Transformations
Utilised in asymmetric synthesis, this compound enables stereoselective reactions. It is a valuable tool for researchers aiming to control the stereochemical outcome of chemical processes.
| Molecular weight | 329.39 |
|---|---|
| Empirical formula | C22H19NO2 |
| Assay | ≥98.0% (sum of enantiomers, TLC) |
| Optical activity | [α]20/D −71±2°, c = 0.5% in chloroform |
| Melting point | 191-196 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Trityl-L-serine lactone used for?
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N-Trityl-L-serine lactone is primarily used as a chiral building block in asymmetric synthesis and peptide chemistry, and as an intermediate for creating complex heterocyclic compounds.
What are the CAS number and molecular formula for N-Trityl-L-serine lactone?
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The CAS number is 88109-06-2, and the molecular formula is C22H19NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Trityl-L-serine lactone with an assay of ≥98.0% (sum of enantiomers, TLC). TSS does not represent this product as USP, BP, EP, or any pharmacopoeia grade.
How should N-Trityl-L-serine lactone be handled safely?
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When handling, use safety equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It is classified with WGK Germany 3.
Is N-Trityl-L-serine lactone suitable for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including N-Trityl-L-serine lactone, adhering to international shipping regulations.
How can I request a sample or quote for N-Trityl-L-serine lactone?
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To request a sample or a quote, please contact our sales team through the website or by direct inquiry, specifying the product CAS number 88109-06-2.
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