5(6)-Carboxytetramethylrhodamine N-succinimidyl ester
5(6)-Carboxytetramethylrhodamine N-succinimidyl ester (CAS: 150408-83-6; Formula: C29H25N3O7; MW: 527.52) is a fluorescent labelling reagent. It is primarily utilised as an amine coupling agent to generate 5(6)-Carboxytetramethylrhodamine (TMR) derivatives, including proteins and pharmaceuticals. This compound is suitable for fluorescence applications, with reported excitation and emission maxima in methanol and phosphate buffers.
Fluorescent Labelling of Biomolecules
Utilised as an amine coupling reagent to covalently attach the TMR fluorophore to proteins and peptides, enabling their detection and tracking in biological systems.
Drug Derivatisation for Research
Serves as a versatile reagent for the derivatisation of amine-containing drug molecules, facilitating their study via fluorescence-based assays.
Membrane and Cellular Probes
The lipophilic nature of TMR derivatives makes them suitable for applications as probes in membrane research and cellular imaging.
| Molecular weight | 527.52 |
|---|---|
| Empirical formula | C29H25N3O7 |
| Assay | ≥70% (coupling to amines) |
| Solubility | DMF: solubleacetonitrile: solublemethanol: soluble |
| Storage temperature | −20°C |
| Application | 5(6)-Carboxytetramethylrhodamine N-succinimidyl ester (TMR-SE) is used as an amine coupling reagent to form 5(6)-carboxytetramethylrhodamine (TMR) derivatized compounds such as proteins and drugs. |
| Suitability | suitable for fluorescence |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Product Line | BioReagent |
|---|---|
| Fluorescence | λex 543 nm; λem 576 nm in methanolλex 554 nm; λem 584 nm in 0.1 M phosphate pH 8.0 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5(6)-Carboxytetramethylrhodamine N-succinimidyl ester used for?
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5(6)-Carboxytetramethylrhodamine N-succinimidyl ester is employed as an amine coupling reagent to create 5(6)-Carboxytetramethylrhodamine (TMR) derivatised compounds, such as proteins and drugs, for fluorescent applications.
What are the CAS number and formula for 5(6)-Carboxytetramethylrhodamine N-succinimidyl ester?
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The CAS number is 150408-83-6 and the empirical formula is C29H25N3O7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥70% (coupling to amines). We do not represent this product as USP, BP, or EP grade.
How should 5(6)-Carboxytetramethylrhodamine N-succinimidyl ester be handled?
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When handling, use appropriate personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Dispose of waste according to regulations; this compound is classified under WGK 3 in Germany.
Is this chemical available for international export?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I obtain a sample or quote for 5(6)-Carboxytetramethylrhodamine N-succinimidyl ester?
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Please contact our sales team via the website or by phone to request a sample or a competitive quote.
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