(4S,5S)-(−)-2-Methyl-5-phenyl-2-oxazoline-4-methanol

CAS 53732-41-5C11H13NO2Chemical Synthesis

(4S,5S)-(−)-2-Methyl-5-phenyl-2-oxazoline-4-methanol (CAS 53732-41-5) is a chiral heterocyclic compound with a molecular weight of 191.23 g/mol. This oxazoline derivative serves as a valuable reagent in asymmetric synthesis, specifically for the stereoselective reduction of ketones to secondary alcohols. Supplied by Tech Serve Solutions, it is a key building block for chemists engaged in complex organic synthesis and the development of enantiomerically pure compounds.

IUPAC: (4S,5S)-(−)-4-Hydroxymethyl-2-methyl-5-phenyloxazoline
Synonyms: C11H13NO2(4S,5S)-(−)-4-Hydroxymethyl-2-methyl-5-phenyloxazoline

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(4S,5S)-(−)-2-Methyl-5-phenyl-2-oxazoline-4-methanol (C11H13NO2) — chemical structure, CAS 53732-41-5; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksOxazolines/Oxazolidines

01 /Applications

Asymmetric Reduction of Ketones

This compound is employed as a chiral auxiliary or reagent in the asymmetric reduction of ketones. It facilitates the stereoselective formation of secondary alcohols, yielding products with high enantiomeric excess.

Chiral Building Block

As a stereochemically defined molecule, it functions as a crucial building block in the synthesis of more complex chiral targets, including pharmaceuticals and natural products.

Heterocyclic Synthesis

Its oxazoline core makes it a useful intermediate for further derivatization and incorporation into various heterocyclic frameworks, expanding synthetic possibilities.

02 /Properties

Molecular weight	191.23
Empirical formula	C11H13NO2
Assay	98%
Optical activity	[α]20/D −172°, c = 10.8 in chloroform
Application	Reagent for the asymmetric reduction of ketones to secondary alcohols.
Melting point	61-65 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

53732-41-5

MDL number

MFCD00064825

PubChem substance

24851283

Beilstein registry

1212843

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (4S,5S)-(−)-2-Methyl-5-phenyl-2-oxazoline-4-methanol used for?

This compound is primarily used as a reagent for the asymmetric reduction of ketones to secondary alcohols and as a chiral building block in organic synthesis.

What is the CAS number and formula for (4S,5S)-(−)-2-Methyl-5-phenyl-2-oxazoline-4-methanol?

The CAS number is 53732-41-5 and the empirical formula is C11H13NO2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications.

How should (4S,5S)-(−)-2-Methyl-5-phenyl-2-oxazoline-4-methanol be handled?

Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound has a WGK rating of 3, indicating significant hazard to water.

Is this compound controlled or scheduled?

The provided data does not indicate that this compound is a controlled or scheduled substance.

How is this chemical packed and exported?

Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, offering secure and compliant packaging for international shipment.