(4S,5R)-(−)-cis-4,5-Diphenyl-2-oxazolidinone

CAS 23204-70-8C15H13NO2Chemical Synthesis

(4S,5R)-(−)-cis-4,5-Diphenyl-2-oxazolidinone (CAS: 23204-70-8) is a chiral auxiliary with the molecular formula C15H13NO2 and a molecular weight of 239.27 g/mol. This compound is instrumental in asymmetric synthesis, facilitating highly diastereoselective reactions. Its primary utility lies in its ability to control stereochemistry in complex organic transformations, making it a valuable reagent for researchers in medicinal chemistry and organic synthesis.

Synonyms: 23204-70-8

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(4S,5R)-(−)-cis-4,5-Diphenyl-2-oxazolidinone (C15H13NO2) — chemical structure, CAS 23204-70-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral AuxiliariesOxazolidinone Derivatives

01 /Applications

Asymmetric Synthesis

Serves as a versatile chiral auxiliary in a range of highly diastereoselective reactions. It is particularly effective in controlling stereochemical outcomes in Michael additions and Diels-Alder reactions.

Chiral Auxiliary

Enables precise stereochemical control in organic synthesis. It is widely employed in cyclopropanations and allylations, allowing for the stereoselective formation of new carbon-carbon bonds.

Organic Synthesis Reagent

Used as a key building block or auxiliary in the synthesis of complex organic molecules. Its chiral nature is leveraged to introduce specific stereocentres with high fidelity.

02 /Properties

Molecular weight	239.27
Empirical formula	C15H13NO2
Assay	98%
Optical activity	[α]23/D −57±4°, c = 2 in chloroform (or methanol)
Application	Versatile chiral auxiliary used in a variety of highly diastereoselective reactions such as Michael additions,1 Diels-Alder reactions,2 cyclopropanations,3 and allylations.4
Melting point	227-232 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

23204-70-8

MDL number

MFCD00799526

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (4S,5R)-(−)-cis-4,5-Diphenyl-2-oxazolidinone used for?

This compound is a versatile chiral auxiliary primarily used in asymmetric synthesis for highly diastereoselective reactions such as Michael additions, Diels-Alder reactions, cyclopropanations, and allylations.

What are the CAS number and formula for this chemical?

The CAS number is 23204-70-8, and the empirical formula is C15H13NO2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product with an assay of 98%. It is supplied as a research or technical grade chemical and is not represented as USP, BP, or EP grade.

How should (4S,5R)-(−)-cis-4,5-Diphenyl-2-oxazolidinone be handled?

Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation to avoid inhaling dust. This compound is classified as an irritant to the skin, eyes, and respiratory tract.