(4S,5R)-(−)-4-Methyl-5-phenyl-2-oxazolidinone

CAS 16251-45-9C10H11NO2Chemical Synthesis

(4S,5R)-(−)-4-Methyl-5-phenyl-2-oxazolidinone (CAS 16251-45-9) is a chiral auxiliary with the molecular formula C10H11NO2 and a molecular weight of 177.20 g/mol. It is primarily employed in asymmetric synthesis for the creation of enantiomerically pure compounds. This oxazolidinone derivative is valued for its effectiveness in stereoselective chemical transformations, enabling precise control over reaction outcomes in complex organic synthesis.

Synonyms: C10H11NO24-Methyl-5-phenyl-2-oxazolidinone

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(4S,5R)-(−)-4-Methyl-5-phenyl-2-oxazolidinone (C10H11NO2) — chemical structure, CAS 16251-45-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral AuxiliariesOxazolidinone Derivatives

01 /Applications

Chiral Auxiliary in Asymmetric Synthesis

This compound serves as a crucial chiral auxiliary, facilitating stereoselective reactions. It is widely used to control the chirality of newly formed stereocenters during synthesis, leading to enantiomerically enriched products.

Synthesis of Enantiopure Compounds

Its specific stereochemical configuration makes it ideal for constructing molecules with defined chirality. It plays a key role in synthetic strategies aimed at producing single enantiomers of complex organic molecules.

Research and Development

As a versatile building block, it is instrumental in academic and industrial R&D settings for exploring novel synthetic routes and developing new chiral compounds.

02 /Properties

Molecular weight	177.20
Empirical formula	C10H11NO2
Assay	99%
Optical activity	[α]25/D −168°, c = 2 in chloroform
Optical purity	ee: 99% (HPLC)
Application	Versatile chiral auxiliary for asymmetric synthesis. For a review, see Aldrichimica Acta.1
Melting point	121-123 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

16251-45-9

MDL number

MFCD00066226

PubChem substance

24860823

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (4S,5R)-(−)-4-Methyl-5-phenyl-2-oxazolidinone used for?

(4S,5R)-(−)-4-Methyl-5-phenyl-2-oxazolidinone is a versatile chiral auxiliary used primarily in asymmetric synthesis to create enantiomerically pure compounds.

What is the CAS number and molecular formula for this product?

The CAS number is 16251-45-9, and the molecular formula is C10H11NO2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this compound with an assay of 99% and optical purity of ee: 99% (HPLC). We do not represent this product as USP, BP, or EP grade.

How should (4S,5R)-(−)-4-Methyl-5-phenyl-2-oxazolidinone be handled?

Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It is classified under WGK 2 in Germany, indicating potential hazards to aquatic environments.

How is this chemical exported and shipped?

Tech Serve Solutions is a global supplier and exporter of fine chemicals. We ensure compliant packaging and shipping procedures for international delivery of this product.