1,11-Diazido-3,6,9-trioxaundecane
1,11-Diazido-3,6,9-trioxaundecane (CAS: 101187-39-7; C8H16N6O3) is a homobifunctional polyethylene glycol (PEG) derivative featuring terminal azide groups. This compound serves as a versatile linker in click chemistry applications, enabling the formation of stable triazole linkages through cycloaddition reactions with alkynes. Its symmetrical structure and reactive azide functionalities make it valuable for crosslinking biomolecules, modifying surfaces, and synthesising complex molecular architectures.
- IUPAC
- Azido-PEG3-azido,Bis-PEG3-Azide
- Synonyms
- Azido-PEG3-azido,Bis-PEG3-Azide
Click Chemistry Linker
Utilised as a homobifunctional PEG azide linker for copper-catalyzed or strain-promoted 1,3-dipolar cycloaddition reactions with terminal alkynes and cyclooctyne derivatives, forming stable triazole bonds.
Bioconjugation
Enables the covalent attachment of biomolecules or surfaces functionalised with alkyne groups, facilitating drug delivery systems, diagnostic tools, and biological probes.
Surface Modification
Azide termini allow for the functionalisation of surfaces pre-activated with alkynes, altering surface properties for applications in materials science and nanotechnology.
Polymer Synthesis
Can be incorporated into polymer chains or used to crosslink polymer networks, introducing PEG segments and enabling further functionalisation via click chemistry.
| Molecular weight | 244.25 |
|---|---|
| Empirical formula | C8H16N6O3 |
| Boiling point | 163-196 °C/760 mmHg |
| Density | 1.170 g/mL at 25 °C |
| Refractive index | n20/D 1.470 |
| Application | Homobifunctional PEG azide click chemistry linker. Azide functional groups will react via a copper catalyzed or strain promoted 1,3-dipolar cycloaddition click reaction with terminal alkynes and cyclooctyne derivatives to yield a stable triazole linkage. |
Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,11-Diazido-3,6,9-trioxaundecane used for?
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1,11-Diazido-3,6,9-trioxaundecane is primarily used as a homobifunctional PEG linker in click chemistry reactions, enabling the conjugation of molecules or surfaces functionalised with alkynes.
What are the CAS number and molecular formula?
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The CAS number for 1,11-Diazido-3,6,9-trioxaundecane is 101187-39-7, and its molecular formula is C8H16N6O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research purposes. The specific assay and grade are detailed on the product specification sheet, and it is not represented as USP, BP, or EP grade.
How should 1,11-Diazido-3,6,9-trioxaundecane be handled safely?
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1,11-Diazido-3,6,9-trioxaundecane is classified with the GHS07 symbol and carries a 'Warning' signal word. It is harmful if swallowed (H302). Always handle with appropriate personal protective equipment and follow standard laboratory safety protocols.
How is this product packed, shipped, and exported?
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Tech Serve Solutions specialises in global supply and export of fine chemicals. Products are carefully packed according to international shipping regulations to ensure safe transit.
How can I request a sample or quote?
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To request a sample or a quotation for 1,11-Diazido-3,6,9-trioxaundecane, please contact our sales team via the website or by telephone.
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