1,10-Phenanthroline monohydrate
1,10-Phenanthroline monohydrate (CAS 5144-89-8), with the empirical formula C12H8N2 · H2O and a molecular weight of 198.22, is a chemical compound primarily utilised in analytical chemistry and biochemistry. When complexed with copper, it exhibits nuclease activity, making it valuable for studying DNA-protein interactions. This JIS special grade reagent is a crucial tool in research laboratories for specific biochemical applications.
- IUPAC
- o-Phenanthroline monohydrate
- Synonyms
- C12H8N2 · H2Oo-Phenanthroline monohydrate
Nuclease Activity Studies
When complexed with copper ions, 1,10-Phenanthroline monohydrate displays nuclease activity. This property is instrumental in biochemical research for investigating DNA-protein interactions and understanding cellular processes at a molecular level.
Analytical Reagent
This compound serves as a valuable reagent in analytical chemistry. Its specific chemical properties allow for its use in various analytical procedures and as a component in chemical synthesis pathways.
Biochemical Research
1,10-Phenanthroline monohydrate is employed in biochemical research as a building block and tool. Its applications extend to studying enzymes and cellular signalling, contributing to a deeper understanding of biological systems.
| Molecular weight | 198.22 |
|---|---|
| Empirical formula | C12H8N2 · H2O |
| Assay | ≥99.0% |
| Grade | JIS special grade |
| Solubility | methanol: soluble200 mM (Stock solution is stable for months at –20° C.) |
| Application | When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions. |
| Melting point | 100-104 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P301IF SWALLOWED
- P501Dispose of contents and container per local regulations
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 25-50/53 |
| Safety statements (S) | 45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Availability | available only in Japan |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,10-Phenanthroline monohydrate used for?
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1,10-Phenanthroline monohydrate is primarily used in biochemical research for its nuclease activity when complexed with copper, which aids in studying DNA-protein interactions. It also serves as a reagent in analytical chemistry and chemical synthesis.
What are the CAS number and formula for 1,10-Phenanthroline monohydrate?
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The CAS number for 1,10-Phenanthroline monohydrate is 5144-89-8, and its empirical formula is C12H8N2 · H2O.
What grade and purity does Tech Serve Solutions supply for 1,10-Phenanthroline monohydrate?
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Tech Serve Solutions supplies 1,10-Phenanthroline monohydrate in JIS special grade with an assay of ≥99.0%. We do not represent this product as USP, BP, or EP grade.
How should 1,10-Phenanthroline monohydrate be handled safely?
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1,10-Phenanthroline monohydrate is toxic if swallowed and toxic to aquatic life with long-lasting effects. Handle with appropriate personal protective equipment, including a dust mask (US N95), eyeshields, face shields, gloves, and a type P2 respirator cartridge. Avoid release into the environment. Refer to the Safety Data Sheet for comprehensive handling information.
Is 1,10-Phenanthroline monohydrate available for export?
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1,10-Phenanthroline monohydrate is available only in Japan, as per the supplier's data.
How can I request a quote or sample for 1,10-Phenanthroline monohydrate?
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To request a quote or sample of 1,10-Phenanthroline monohydrate, please contact the Tech Serve Solutions sales team through our official website or designated contact channels.
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