5-Amino-3-(4-chlorophenyl)pyrazole
5-Amino-3-(4-chlorophenyl)pyrazole (CAS: 78583-81-0) is a halogenated heterocyclic organic compound with the molecular formula C9H8ClN3 and a molecular weight of 193.63 g/mol. It serves as a valuable building block in chemical synthesis, particularly within the pharmaceutical and agrochemical industries. Its structure, featuring a pyrazole core and a chlorophenyl substituent, makes it a useful intermediate for creating more complex molecules with diverse biological activities.

Pharmaceutical Intermediate
This compound is frequently employed as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its pyrazole scaffold is present in numerous therapeutic agents, and the chlorophenyl group offers a site for further chemical modification.
Agrochemical Synthesis
The structural features of 5-Amino-3-(4-chlorophenyl)pyrazole lend themselves to the development of novel agrochemicals, including herbicides, fungicides, and insecticides, by serving as a foundational component in their synthetic pathways.
Research and Development
As a versatile building block, it is utilised in academic and industrial research laboratories for exploring new synthetic methodologies and discovering novel compounds with potential applications in materials science and medicinal chemistry.
| Molecular weight | 193.63 |
|---|---|
| Empirical formula | C9H8ClN3 |
| Assay | 97% |
| Melting point | 172-176 °C(lit.) |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Amino-3-(4-chlorophenyl)pyrazole used for?
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5-Amino-3-(4-chlorophenyl)pyrazole is primarily used as a building block and intermediate in the synthesis of pharmaceuticals and agrochemicals, as well as in general chemical research and development.
What are the CAS number and formula for 5-Amino-3-(4-chlorophenyl)pyrazole?
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The CAS number for 5-Amino-3-(4-chlorophenyl)pyrazole is 78583-81-0, and its empirical formula is C9H8ClN3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Amino-3-(4-chlorophenyl)pyrazole with an assay of 97%. This product is suitable for research and synthesis; TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
What are the main hazards associated with this chemical?
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This compound is classified as Dangerous. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shield, and gloves, must be worn.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions, a global supplier and exporter since 1998, packages and ships chemicals in compliance with international regulations for safe transport. Specific packaging details can be provided upon request.
How can I request a sample or a quote for 5-Amino-3-(4-chlorophenyl)pyrazole?
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To request a sample or obtain a quote, please contact our sales department via the website or direct email, providing your specific requirements and shipping information.
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