(4R)-Boc-4-benzyl-Pyr-OBzl
(4R)-Boc-4-benzyl-Pyr-OBzl, CAS 203645-44-7, is a protected pyroglutamic acid derivative with the molecular formula C24H27NO5 and a molecular weight of 409.47 g/mol. This chiral compound serves as a valuable building block in organic synthesis, particularly within peptide chemistry and the development of unnatural amino acids. Its specific stereochemistry and protected functional groups make it suitable for complex molecular assembly and the creation of novel chemical entities for research purposes.
- IUPAC
- (4R)-Boc-4-benzyl-L-pyroglutamic acid benzyl ester,Benzyl (2S,4R)-1-Boc-4-benzyl-5-oxo-2-pyrrolidinecarboxylate
- Synonyms
- Benzyl (2S,4R)-1-Boc-4-benzyl-5-oxo-2-pyrrolidinecarboxylate

Peptide Synthesis
Serves as a protected unnatural amino acid derivative for incorporation into peptide chains. Its specific chiral centre and protecting groups facilitate controlled peptide elongation in solid-phase or solution-phase synthesis.
Organic Synthesis Building Block
A versatile intermediate for the construction of complex organic molecules. The protected pyroglutamate core allows for selective functionalization and elaboration in multi-step synthetic pathways.
Chemical Biology Research
Utilised in the synthesis of modified peptides or peptidomimetics for probing biological systems. Its structure can be tailored for applications in drug discovery or biochemical assays.
Development of Novel Compounds
Facilitates the synthesis of unnatural amino acid derivatives and analogues, expanding the chemical space for materials science and medicinal chemistry research.
| Molecular weight | 409.47 |
|---|---|
| Empirical formula | C24H27NO5 |
| Assay | ≥96.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (4R)-Boc-4-benzyl-Pyr-OBzl used for?
+
(4R)-Boc-4-benzyl-Pyr-OBzl is used as a protected building block in peptide synthesis, a chiral intermediate in organic synthesis, and in chemical biology research for the development of novel compounds and unnatural amino acid derivatives.
What are the CAS number and formula for (4R)-Boc-4-benzyl-Pyr-OBzl?
+
The CAS number is 203645-44-7 and the empirical formula is C24H27NO5.
What grade and purity does Tech Serve Solutions supply for (4R)-Boc-4-benzyl-Pyr-OBzl?
+
Tech Serve Solutions supplies (4R)-Boc-4-benzyl-Pyr-OBzl with an assay of ≥96.0% (HPLC). This product is supplied for research and development purposes and is not intended for USP, BP, EP, or pharmaceutical use.
How should (4R)-Boc-4-benzyl-Pyr-OBzl be handled safely?
+
Handle (4R)-Boc-4-benzyl-Pyr-OBzl with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended for respiratory protection. Ensure adequate ventilation. Refer to the Safety Data Sheet (SDS) for comprehensive safety information.
Is (4R)-Boc-4-benzyl-Pyr-OBzl a controlled substance?
+
The provided data does not indicate that (4R)-Boc-4-benzyl-Pyr-OBzl is a controlled substance.
How is (4R)-Boc-4-benzyl-Pyr-OBzl packed, shipped, and exported?
+
(4R)-Boc-4-benzyl-Pyr-OBzl is carefully packed according to industry standards to ensure integrity during transit. Tech Serve Solutions has extensive experience in exporting fine chemicals globally to research institutions and chemical companies.
How can I request a sample or quote for (4R)-Boc-4-benzyl-Pyr-OBzl?
+
To request a sample or a quote for (4R)-Boc-4-benzyl-Pyr-OBzl, please contact our sales department through the website or by email, providing your details and the quantity required.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis