(4R)-Boc-4-(4-methylbenzyl)-Pyr-OBzl
(4R)-Boc-4-(4-methylbenzyl)-Pyr-OBzl (CAS: 401813-50-1), with the empirical formula C25H29NO5 and a molecular weight of 423.50 g/mol, is a specialised pyroglutamine derivative. It is primarily utilised in chemical synthesis, particularly within the fields of chemical biology and peptide chemistry. This unnatural amino acid derivative serves as a valuable building block for researchers developing complex molecules and novel peptide structures, offering precise stereochemical control.
- IUPAC
- (4R)-Boc-4-(4-methylbenzyl)-L-pyroglutamic acid benzyl ester,Benzyl (2S,4R)-1-Boc-4-(4-methylbenzyl)-5-oxo-2-pyrrolidinecarboxylate

Peptide Synthesis
This compound acts as a protected unnatural amino acid building block, essential for the incorporation of modified residues into peptide chains. It facilitates the synthesis of peptides with specific structural or functional properties.
Chemical Biology Research
As a derivative of pyroglutamic acid, it can be employed in probing biological pathways or as a component in the development of peptidomimetics. Its unique structure aids in studying protein-ligand interactions.
Organic Synthesis Intermediate
The molecule serves as a versatile intermediate in complex organic synthesis, allowing for the construction of diverse molecular architectures. Its protected functional groups enable selective chemical transformations.
| Molecular weight | 423.50 |
|---|---|
| Empirical formula | C25H29NO5 |
| Assay | ≥96.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (4R)-Boc-4-(4-methylbenzyl)-Pyr-OBzl used for?
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(4R)-Boc-4-(4-methylbenzyl)-Pyr-OBzl is used in chemical synthesis, chemical biology, and peptide chemistry as a building block for constructing complex molecules and modified peptides.
What is the CAS number and formula for this product?
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The CAS number is 401813-50-1, and the empirical formula is C25H29NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (4R)-Boc-4-(4-methylbenzyl)-Pyr-OBzl with a purity of ≥96.0% (HPLC). This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should I handle (4R)-Boc-4-(4-methylbenzyl)-Pyr-OBzl safely?
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Safety precautions include using eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if respiratory protection is needed. The compound is classified under WGK Germany 3, indicating a high hazard to water.
How is this chemical packed and shipped?
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This chemical is carefully packed and exported by Tech Serve Solutions, adhering to international shipping regulations for fine chemicals. Specific packaging details can be provided upon request.
How can I request a quote or sample?
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To request a quote or a sample of (4R)-Boc-4-(4-methylbenzyl)-Pyr-OBzl, please contact our sales team through the TSS website or via email, providing your specific requirements.
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