Hydroquinine
Hydroquinine (CAS 522-66-7), a cinchona alkaloid with the molecular formula C20H26N2O2, is a key compound in asymmetric synthesis. This chiral molecule is valued for its specific stereochemistry, enabling its use in stereoselective chemical transformations. Hydroquinine finds application in research and development for creating enantiomerically pure compounds, particularly in the pharmaceutical and fine chemical industries.
- IUPAC
- (8a,9R)-10,11-Dihydro-6′-methoxycinchonan-9-ol,Dihydroquinine,NSC 41799
Asymmetric Synthesis
Hydroquinine serves as a chiral auxiliary or catalyst component in asymmetric synthesis, facilitating the creation of enantiomerically enriched products. Its defined stereocenters are crucial for directing stereochemical outcomes in various organic reactions.
Chiral Ligand Development
As a cinchona alkaloid derivative, hydroquinine can be a precursor for developing specialized chiral ligands. These ligands are essential for metal-catalyzed asymmetric transformations, enhancing enantioselectivity.
Research and Development
Used in academic and industrial research settings, hydroquinine is employed to explore new synthetic methodologies and to produce complex chiral molecules. Its biological activity also makes it a subject of study in medicinal chemistry.
| Molecular weight | 326.43 |
|---|---|
| Empirical formula | C20H26N2O2 |
| Assay | ≥95.0% (sum of enantiomers, HPLC) |
| Optical activity | [α]20/D −143±5°, c = 1% in ethanol (dry matter) |
| Loss on drying | ≤1% loss on drying, 110 °C |
| Melting point | 168-176 °C(lit.)168-176 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CYP2D6(1565) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hydroquinine used for?
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Hydroquinine is primarily used in asymmetric synthesis and as a component in the development of chiral ligands for stereoselective chemical reactions. It is also utilized in research and development for creating enantiomerically pure compounds.
What are the CAS number and formula for Hydroquinine?
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The CAS number for Hydroquinine is 522-66-7, and its molecular formula is C20H26N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Hydroquinine with an assay of ≥95.0% (sum of enantiomers, HPLC). We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should Hydroquinine be handled safely?
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Hydroquinine is a warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Ensure adequate ventilation.
Can Tech Serve Solutions export Hydroquinine?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Hydroquinine, and can fulfil export orders worldwide.
How can I request a quote or sample for Hydroquinine?
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Please contact our sales team via the website or direct inquiry channels to request a quote or a sample of Hydroquinine.
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