(4R)-2-Hydroxy-5,5-dimethyl-4-phenyl-1,3,2-dioxaphosphorinan 2-oxide
(4R)-2-Hydroxy-5,5-dimethyl-4-phenyl-1,3,2-dioxaphosphorinan 2-oxide (CAS 98674-80-7), a chiral organophosphate compound with the formula C11H15O4P and a molecular weight of 242.21 g/mol. This chemical is primarily utilised as a valuable building block in asymmetric synthesis and chiral resolution processes. Its defined stereochemistry makes it suitable for applications requiring precise molecular architecture.
- IUPAC
- (2R,4R)-5,5-Dimethyl-2-hydroxy-4-phenyl-1,3,2-dioxaphosphorinan 2-oxide,(R)-(−)-2-Hydroxy-5,5-dimethyl-4-phenyl-1,3,2-dioxaphosphorinane 2-oxide
- Synonyms
- 2-dioxaphosphorinan 2-oxideC11H15O4P(2R,4R)-5,5-Dimethyl-2-hydroxy-4-phenyl-1,3,2-dioxaphosphorinan 2-oxide(R)-(−)-2-Hydroxy-5,5-dimethyl-4-phenyl-1,3,2-dioxaphosphorinane 2-oxide
Asymmetric Synthesis
This chiral dioxaphosphorinan derivative serves as a crucial building block for constructing complex molecules with specific stereocentres. Its defined configuration aids in enantioselective transformations.
Chiral Resolution Reagent
It can be employed in the separation of racemic mixtures, facilitating the isolation of desired enantiomers in pharmaceutical and fine chemical synthesis.
Organic Synthesis Intermediate
As an organic building block, it provides a functionalised chiral scaffold for the synthesis of diverse organic compounds. Its phosphorus-containing structure offers unique reactivity.
| Molecular weight | 242.21 |
|---|---|
| Empirical formula | C11H15O4P |
| Assay | ≥98.0% (calc. based on dry substance, T) |
| Optical activity | [α]20/D −62±3°, c = 0.5% in methanol |
| Storage temperature | 2-8°C |
| Impurities tested | ≤4% water |
| Melting point | 224-227 °C(lit.)224-227 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (4R)-2-Hydroxy-5,5-dimethyl-4-phenyl-1,3,2-dioxaphosphorinan 2-oxide used for?
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(4R)-2-Hydroxy-5,5-dimethyl-4-phenyl-1,3,2-dioxaphosphorinan 2-oxide is primarily used in asymmetric synthesis and as a chiral resolution reagent.
What is the CAS number and chemical formula for this compound?
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The CAS number is 98674-80-7, and the chemical formula is C11H15O4P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥98.0% (calculated based on dry substance). We do not represent this product as USP, BP, or EP grade.
How should this chemical be handled safely?
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This compound is a Warning irritant (H315, H319, H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 or equivalent). Ensure adequate ventilation.
How is this chemical packed, shipped, and exported?
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This chemical is carefully packed to maintain its integrity during transport and is available for global export by Tech Serve Solutions, a specialist supplier since 1998.
How can I request a sample or quote?
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Please contact Tech Serve Solutions directly through our website or by phone to request a sample or a competitive quote for (4R)-2-Hydroxy-5,5-dimethyl-4-phenyl-1,3,2-dioxaphosphorinan 2-oxide.
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