4-Trifluoromethylumbelliferyl glucuronide potassium salt
4-Trifluoromethylumbelliferyl glucuronide potassium salt (CAS: 143547-78-8) is a fluorogenic substrate with the molecular formula C16H12F3O9K and a molecular weight of 444.35. This compound is primarily utilised in biochemical research and molecular biology. It serves as a sensitive tool for detecting glucuronidase enzyme activity, making it valuable in various enzymatic assays and studies related to glycobiology and post-translational modifications. Its fluorogenic nature allows for quantitative analysis.
- IUPAC
- 4-Trifluoromethyl-7-hydroxycoumarin glucuronide

Enzyme Activity Assays
This compound acts as a fluorogenic substrate for the enzyme glucuronidase. Upon enzymatic cleavage, it releases a fluorescent product, allowing for sensitive detection and quantification of enzyme activity in various biological samples.
Biochemical Research
It is employed in fundamental research concerning glycobiology, post-translational modifications, and proteomics. Researchers utilise it to study the function and regulation of glucuronidases in cellular processes.
Molecular Biology Applications
The substrate is valuable in molecular biology for applications requiring the detection of glucuronidase activity, such as in reporter gene assays or for monitoring enzyme expression levels.
| Molecular weight | 444.35 |
|---|---|
| Linear formula | C16H12F3O9K |
| Assay | ≥98% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Trifluoromethylumbelliferyl glucuronide potassium salt used for?
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4-Trifluoromethylumbelliferyl glucuronide potassium salt is primarily used as a fluorogenic substrate for detecting and quantifying glucuronidase enzyme activity in biochemical and molecular biology research.
What is the CAS number and chemical formula?
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The CAS number is 143547-78-8, and the chemical formula is C16H12F3O9K.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥98% (TLC). We do not represent this product as USP, BP, or EP grade.
What safety precautions should be taken when handling this chemical?
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When handling, wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is also recommended. This compound has a WGK rating of 3 in Germany, indicating it is hazardous to water.
How is this chemical typically packed and shipped?
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This chemical is carefully packed to maintain its integrity during transit and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales department through the website or by calling our customer service line.
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