4-Thiouridine

CAS 13957-31-8C9H12N2O5SBiochemicals & Reagents

4-Thiouridine (CAS: 13957-31-8; Formula: C9H12N2O5S; MW: 260.27) is a photoreactive uridine analogue supplied by TSS. It can be incorporated into RNA structures upon phosphorylation to 4-thioUTP. This compound is valuable for investigating the specificity and kinetics of uridine-cytidine kinases and for studying RNA-protein interactions through crosslinking. It is typically stored at -20°C.

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4-Thiouridine (C9H12N2O5S) — chemical structure, CAS 13957-31-8; Life Science, fine chemical supplied by Tech Serve Solutions

Biochemicals and ReagentsNucleoside AnalogsNucleosidesNucleotidesOligonucleotides

01 /Applications

RNA Research

Incorporated into RNA after phosphorylation to 4-thioUTP, 4-Thiouridine serves as a photoreactive crosslinking agent for studying RNA structures and interactions.

Enzyme Kinetics

Utilised to investigate the specificity and kinetics of uridine-cytidine kinases, aiding in understanding enzyme mechanisms.

Biochemical Studies

As a modified nucleoside, it is employed in various biochemical assays and for the synthesis of modified oligonucleotides.

02 /Properties

Molecular weight	260.27
Empirical formula	C9H12N2O5S
Assay	≥98%
Storage temperature	−20°C
Application	4-Thiouridine is a photoreactive (crosslinking) uridine analogue that upon phosphorylation to 4-thioUTP may be incorporated into RNA structures. 4-Thiouridine may be used to study the specificity and kinetics of uridine-cytidine kinases.

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

13957-31-8

MDL number

MFCD00006538

PubChem substance

24900212

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-Thiouridine primarily used for?

4-Thiouridine is primarily used as a photoreactive analogue for studying RNA structures, RNA-protein crosslinking, and investigating the kinetics of uridine-cytidine kinases.

What is the CAS number and chemical formula for 4-Thiouridine?

The CAS number for 4-Thiouridine is 13957-31-8, and its chemical formula is C9H12N2O5S.

What grade and purity does Tech Serve Solutions supply for 4-Thiouridine?

Tech Serve Solutions supplies 4-Thiouridine with an assay of ≥98%. We do not represent this product as USP, BP, or EP grade.

How should 4-Thiouridine be handled and stored?

Handle 4-Thiouridine with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. It should be stored at -20°C.

Is 4-Thiouridine a controlled substance?

The provided data does not indicate that 4-Thiouridine is a controlled substance.

How is 4-Thiouridine shipped and exported?

4-Thiouridine is professionally packed and exported by Tech Serve Solutions, a specialist global supplier, adhering to international shipping regulations for chemicals.