4-Nitrophenol
4-Nitrophenol (CAS: 100-02-7, Formula: O2NC6H4OH) is a pale yellow crystalline solid with a molecular weight of 139.11 g/mol. As a versatile organic building block, it finds application in the synthesis of various organic compounds. This compound requires careful handling due to its hazardous properties and is typically stored under refrigeration.
- IUPAC
- p-Nitrophenol
- Synonyms
- p-Nitrophenol4-HydroxynitrobenzenePhenol, 4-nitro-
Chemical Synthesis Intermediate
4-Nitrophenol serves as a key intermediate in organic synthesis. Its nitro and phenol groups allow for diverse chemical transformations, making it valuable in the production of pharmaceuticals, dyes, and other speciality chemicals.
Precursor for Paracetamol Synthesis
It is a crucial precursor in the industrial synthesis of paracetamol (acetaminophen), a widely used analgesic and antipyretic medication.
Reagent in Analytical Chemistry
4-Nitrophenol is used as a pH indicator due to the distinct colour change of its conjugate base (4-nitrophenolate ion) in alkaline solutions.
Production of Pesticides and Herbicides
This compound is employed in the manufacturing process of certain agricultural chemicals, including insecticides and herbicides, contributing to crop protection.
| Molecular weight | 139.11 |
|---|---|
| Linear formula | O2NC6H4OH |
| Grade | purum |
| Boiling point | 279 °C(lit.) |
| Concentration | 10 mM |
| Vapour pressure | 0.6 mmHg (120 °C) |
| Autoignition temp | 541 °F |
| Melting point | 110-115 °C(lit.) |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
- H373May cause damage to organs through prolonged exposure
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Flash point | 169 °C / 336.2 °F |
| Transport (UN / ADR) | UN 1663 6.1 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-33 |
| Safety statements (S) | 28 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Nitrophenol used for?
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4-Nitrophenol is primarily used as an intermediate in the synthesis of pharmaceuticals like paracetamol, dyes, pesticides, and as a pH indicator.
What are the CAS number and formula for 4-Nitrophenol?
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The CAS number for 4-Nitrophenol is 100-02-7, and its chemical formula is O2NC6H4OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Nitrophenol in 'purum' grade. We do not represent this product as USP, BP, or EP grade.
How should 4-Nitrophenol be handled safely?
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4-Nitrophenol is harmful if swallowed, in contact with skin, or if inhaled, and may cause damage to organs through prolonged or repeated exposure (H302, H312, H332, H373). Always use appropriate personal protective equipment, including a dust mask, gloves, and eye/face protection.
How is 4-Nitrophenol packed and shipped?
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4-Nitrophenol is packed according to international shipping regulations, including UN 1663 classification for hazardous materials. We export globally.
How can I request a sample or quote for 4-Nitrophenol?
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To request a sample or obtain a quote for 4-Nitrophenol, please contact our sales department via the website or direct inquiry.
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