4-Nitrophenethyl bromide
4-Nitrophenethyl bromide (CAS 5339-26-4), with the molecular formula O2NC6H4CH2CH2Br and a molecular weight of 230.06 g/mol, is a key organic building block. It is primarily utilised in biochemical research as a substrate for enzyme kinetic studies, particularly for investigating hGST T1-1 variants. This compound serves as a valuable reagent in chemical synthesis, offering a nitro-functionalized phenethyl bromide moiety for further elaboration in organic chemistry.
- IUPAC
- 1-(2-Bromoethyl)-4-nitrobenzene,2-(4-Nitrophenyl)ethyl bromide
- Synonyms
- 1-(2-Bromoethyl)-4-nitrobenzene2-(4-Nitrophenyl)ethyl bromide
Enzyme Kinetic Studies
Utilised as a substrate for determining kinetic parameters such as Km and Kcat for various GST T1-1 enzyme variants. This application is crucial for understanding enzyme mechanisms and inhibitor profiling.
Organic Synthesis Reagent
Serves as a versatile building block in organic synthesis, providing a 4-nitrophenethyl group for constructing more complex molecules. Its structure allows for various functional group transformations and coupling reactions.
Biochemical Research Tool
Employed in research settings to probe enzyme activity and substrate specificity within biological systems. Its specific reactivity makes it useful for mechanistic investigations.
| Molecular weight | 230.06 |
|---|---|
| Linear formula | O2NC6H4CH2CH2Br |
| Assay | 98% |
| Application | 4-nitrophenethyl bromide is used a s a GST T1-1 substrate for identifying many kinetic parameters (Km, Kcat) for hGST T1-1 variants1. |
| Melting point | 67-69 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Nitrophenethyl bromide used for?
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4-Nitrophenethyl bromide is primarily used as a substrate in biochemical research for determining enzyme kinetic parameters, such as Km and Kcat for hGST T1-1 variants. It also functions as a versatile building block in organic synthesis.
What is the CAS number and formula for 4-Nitrophenethyl bromide?
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The CAS number is 5339-26-4 and the linear formula is O2NC6H4CH2CH2Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Nitrophenethyl bromide with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
What are the main safety hazards associated with 4-Nitrophenethyl bromide?
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4-Nitrophenethyl bromide is classified as a warning substance. It can cause skin irritation (H315), allergic skin reaction (H317), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shields, and gloves, should be used during handling.
Is 4-Nitrophenethyl bromide controlled or scheduled?
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The provided data does not indicate that 4-Nitrophenethyl bromide is a controlled or scheduled substance.
How is 4-Nitrophenethyl bromide packed, shipped, and exported?
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4-Nitrophenethyl bromide is carefully packed according to industry standards to ensure safe transit and is exported globally by Tech Serve Solutions.
How can I request a quote or sample of 4-Nitrophenethyl bromide?
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To request a quote or sample, please contact our sales department through the website or by phone, providing your requirements and shipping details.
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