4-Nitroindole-3-carboxaldehyde
4-Nitroindole-3-carboxaldehyde (CAS: 10553-11-4; Formula: C9H6N2O3; MW: 190.16) is a versatile organic building block and indole derivative supplied by Tech Serve Solutions. This compound is characterised by its nitro and aldehyde functionalities on the indole core, making it a valuable intermediate in complex organic synthesis. Its primary applications lie in the preparation of diverse heterocyclic compounds and biologically active molecules, particularly within pharmaceutical research and materials science.
- IUPAC
- 3-Formyl-4-nitroindole

Synthesis of Anticancer Immunomodulators
Utilised as a key reactant in the synthesis of tryptophan dioxygenase inhibitors, which are investigated for their potential as anticancer immunomodulators.
Preparation of Thaxtomin Analogs
Serves as a reactant in the preparation of structural analogues of thaxtomin, contributing to research in agrochemical or biological studies.
Chromophore Development
Employed in the preparation of chromophores associated with gold fluorescent proteins, relevant for advanced materials and imaging applications.
Brassinin and Gramine Derivatives
Acts as a reactant in the preparation of brassinin and gramine derivatives, important classes of natural products and synthetic intermediates.
| Molecular weight | 190.16 |
|---|---|
| Empirical formula | C9H6N2O3 |
| Assay | 97% |
| Application | • reactant in synthesis of tryptophan dioxygenase inhibitors as potential anticancer immunomodulators1• reactant in synthesis of structural analogs of thaxtomin2• reactant in preparation of chromophores related to gold fluorescent protein3• reactant in preparation of brassinin and gramine derivatives4 |
| Melting point | 189-193 °C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Nitroindole-3-carboxaldehyde used for?
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4-Nitroindole-3-carboxaldehyde is used as a reactant in the synthesis of various compounds, including potential anticancer immunomodulators, structural analogs of thaxtomin, chromophores for fluorescent proteins, and brassinin and gramine derivatives. It is a key building block in organic synthesis.
What is the CAS number and formula for 4-Nitroindole-3-carboxaldehyde?
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The CAS number for 4-Nitroindole-3-carboxaldehyde is 10553-11-4, and its molecular formula is C9H6N2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Nitroindole-3-carboxaldehyde with an assay of 97%. This is a research-grade material, and TSS does not represent it as USP, BP, or EP grade.
How should 4-Nitroindole-3-carboxaldehyde be handled safely?
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Handling requires a dust mask type N95 (US), eyeshields, faceshields, and gloves due to hazards including harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Ensure good ventilation and avoid breathing dust.
Is 4-Nitroindole-3-carboxaldehyde a controlled substance?
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Based on the provided data, there is no indication that 4-Nitroindole-3-carboxaldehyde is a controlled substance.
How is 4-Nitroindole-3-carboxaldehyde packed and shipped?
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Tech Serve Solutions exports chemicals globally. Specific packing and shipping details for 4-Nitroindole-3-carboxaldehyde are available upon request to meet regulatory and customer requirements.
How can I request a sample or quote for 4-Nitroindole-3-carboxaldehyde?
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To request a sample or quote for 4-Nitroindole-3-carboxaldehyde, please contact the Tech Serve Solutions sales team through our website or by phone.
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