4-Nitrobenzyl bromide
4-Nitrobenzyl bromide (CAS: 100-11-8), with the molecular formula O2NC6H4CH2Br and a molecular weight of 216.03 g/mol, is a key organic compound. It functions primarily as a derivatization reagent in analytical chemistry, particularly for chromatography, and serves as a versatile building block in chemical synthesis. Its ability to introduce the 4-nitrobenzyl group makes it valuable for modifying molecules for detection or further reaction.
- IUPAC
- α-Bromo-4-nitrotoluene
- Synonyms
- α-Bromo-4-nitrotoluene1-(Bromomethyl)-4-nitrobenzene
Derivatization Reagent
4-Nitrobenzyl bromide is employed to derivatize various analytes, enhancing their detectability in chromatographic methods like HPLC. The introduced nitro group offers a strong chromophore for UV-Vis detection.
Organic Synthesis Building Block
This compound serves as a useful precursor in the synthesis of more complex organic molecules. The reactive benzyl bromide functionality allows for facile alkylation reactions.
Analytical Chemistry
Used in analytical laboratories for specific derivatization protocols, aiding in the identification and quantification of certain chemical species.
| Molecular weight | 216.03 |
|---|---|
| Linear formula | O2NC6H4CH2Br |
| Assay | 99% |
| Melting point | 96-99 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Nitrobenzyl bromide used for?
+
4-Nitrobenzyl bromide is primarily used as a derivatization reagent in analytical chemistry, especially for HPLC, and as a building block in organic synthesis.
What is the CAS number and chemical formula for 4-Nitrobenzyl bromide?
+
The CAS number is 100-11-8 and the chemical formula is O2NC6H4CH2Br.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 4-Nitrobenzyl bromide with an assay of 99%. This product is not classified as USP, BP, or EP grade.
How should 4-Nitrobenzyl bromide be handled safely?
+
4-Nitrobenzyl bromide is a danger to health, causing severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including eyeshields, face shields, chemical-resistant gloves, and respiratory protection suitable for fine dusts or mists. Ensure adequate ventilation and immediate access to eyewash stations and safety showers.
How is 4-Nitrobenzyl bromide packed and shipped?
+
4-Nitrobenzyl bromide is packed in accordance with international shipping regulations for hazardous materials. It is shipped globally by Tech Serve Solutions, a specialist exporter.
How can I request a sample or quote for 4-Nitrobenzyl bromide?
+
Please contact Tech Serve Solutions directly through our website or by phone to request a sample or a quotation for 4-Nitrobenzyl bromide.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis