1-(Fmoc-amino)cyclobutanecarboxylic acid
1-(Fmoc-amino)cyclobutanecarboxylic acid (CAS: 885951-77-9) is a protected alicyclic amino acid with the molecular formula C20H19NO4 and a molecular weight of 337.37 g/mol. Utilised in chemical synthesis and peptide chemistry, it serves as a valuable building block for introducing cyclobutane ring structures into peptides and other complex molecules. Its Fmoc protecting group facilitates controlled synthetic strategies.
- IUPAC
- Fmoc-cyclovaline
- Synonyms
- Fmoc-cyclovaline

Peptide Synthesis
Incorporates a rigid cyclobutane moiety into peptide sequences, influencing secondary structure and stability. The Fmoc group allows for standard solid-phase peptide synthesis protocols.
Chemical Biology Research
Serves as a tool for probing protein structure-function relationships by introducing conformational constraints through the alicyclic ring system.
Organic Synthesis Intermediate
A versatile building block for the construction of complex organic molecules and unnatural amino acid derivatives. Its unique structure can impart specific properties to target compounds.
| Molecular weight | 337.37 |
|---|---|
| Empirical formula | C20H19NO4 |
| Assay | ≥95.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(Fmoc-amino)cyclobutanecarboxylic acid used for?
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1-(Fmoc-amino)cyclobutanecarboxylic acid is primarily used as a protected building block in peptide synthesis and as an intermediate in organic and chemical biology research for introducing alicyclic structures.
What is the CAS number and formula for 1-(Fmoc-amino)cyclobutanecarboxylic acid?
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The CAS number is 885951-77-9 and the empirical formula is C20H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(Fmoc-amino)cyclobutanecarboxylic acid with a purity of ≥95.0% (HPLC). This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should 1-(Fmoc-amino)cyclobutanecarboxylic acid be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Ensure adequate ventilation. The compound is classified under WGK Germany 3.
How is 1-(Fmoc-amino)cyclobutanecarboxylic acid packed and shipped?
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This chemical is stored at 2-8°C. Tech Serve Solutions professionally packs and exports chemicals globally, adhering to all necessary regulations for safe transport.
How can I request a sample or quote for 1-(Fmoc-amino)cyclobutanecarboxylic acid?
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To request a sample or a quotation, please contact our sales team through the website or by phone, providing the product name and CAS number (885951-77-9).
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