5-Aminoisophthalic acid
5-Aminoisophthalic acid (CAS: 99-31-0, Formula: H2NC6H3-1,3-(CO2H)2, Molar Mass: 181.15 g/mol) is an aromatic amino acid derivative with a unique structure featuring both amine and carboxylic acid functionalities on a benzene ring. This compound serves as a valuable intermediate in chemical synthesis and finds applications in areas such as chemical biology and peptide chemistry, particularly in the development of unnatural amino acid derivatives.
- IUPAC
- 5-Aminobenzene-1,3-dicarboxylic acid
- Synonyms
- 5-Aminobenzene-1,3-dicarboxylic acid

Chemical Synthesis Intermediate
5-Aminoisophthalic acid is utilised as a building block in the synthesis of more complex organic molecules. Its dual functional groups allow for diverse chemical transformations, making it useful for creating novel compounds.
Peptide Chemistry and Unnatural Amino Acids
This compound is employed in peptide chemistry for the incorporation of unnatural amino acid derivatives. It can be integrated into peptide chains to modify their structure and function for research purposes.
Research and Development
Primarily used in laboratory settings, 5-Aminoisophthalic acid supports research in chemical biology and materials science. Its specific structure is leveraged for developing new reagents and exploring molecular interactions.
| Molecular weight | 181.15 |
|---|---|
| Linear formula | H2NC6H3-1,3-(CO2H)2 |
| Assay | 94% |
| Melting point | >300 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Aminoisophthalic acid used for?
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5-Aminoisophthalic acid is primarily used as an intermediate in chemical synthesis, a building block for unnatural amino acid derivatives in peptide chemistry, and in research for chemical biology.
What are the CAS number and formula for 5-Aminoisophthalic acid?
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The CAS number for 5-Aminoisophthalic acid is 99-31-0, and its linear formula is H2NC6H3-1,3-(CO2H)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Aminoisophthalic acid with an assay of 94%. This product is not tested or intended for USP, BP, EP, or other pharmacopoeia grades, nor for food, nutraceutical, or medicinal use.
How should 5-Aminoisophthalic acid be handled safely?
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5-Aminoisophthalic acid is a Warning substance, classified with H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust.
Is 5-Aminoisophthalic acid a controlled substance?
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The provided data does not indicate that 5-Aminoisophthalic acid is a controlled substance.
How is 5-Aminoisophthalic acid shipped and exported?
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Tech Serve Solutions, a global supplier and exporter since 1998, ships and exports fine chemicals like 5-Aminoisophthalic acid in compliance with international regulations for chemical transport.
How can I request a sample or quote for 5-Aminoisophthalic acid?
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To request a sample or a quote for 5-Aminoisophthalic acid, please contact our sales team through the provided channels on the Tech Serve Solutions website.
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