5-Aminomethyl-7-chloro-1,3-benzodioxole hydrochloride
5-Aminomethyl-7-chloro-1,3-benzodioxole hydrochloride (CAS: 350480-53-4) is a halogenated heterocyclic organic compound with a molecular weight of 222.07 g/mol. This chemical serves as a valuable building block in organic synthesis, particularly for creating more complex molecules within pharmaceutical and chemical research sectors. Its structure, featuring a benzodioxole core with a chloro substituent and an aminomethyl group, makes it useful in medicinal chemistry and materials science.
- IUPAC
- 7-Chloro-1,3-benzodioxole-5-methylamine hydrochloride
- Synonyms
- 7-Chloro-1,3-benzodioxole-5-methylamine hydrochloride

Organic Synthesis Intermediate
This compound is utilized as a key intermediate in multi-step organic synthesis pathways. Its functional groups allow for various chemical transformations, enabling the construction of novel molecular architectures.
Pharmaceutical Research and Development
As a heterocyclic building block, it is employed in the design and synthesis of potential drug candidates. The chloro-benzodioxole moiety can be incorporated into molecules to modulate their pharmacological properties.
Medicinal Chemistry
Researchers in medicinal chemistry may use this compound to explore structure-activity relationships (SAR) in the development of new therapeutic agents.
| Molecular weight | 222.07 |
|---|---|
| Empirical formula | C8H8ClNO2 · HCl |
| Assay | 95% |
| Melting point | 212-218 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Aminomethyl-7-chloro-1,3-benzodioxole hydrochloride used for?
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5-Aminomethyl-7-chloro-1,3-benzodioxole hydrochloride is primarily used as a building block in organic synthesis and for research and development in pharmaceutical chemistry.
What are the CAS number and molecular formula?
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The CAS number is 350480-53-4, and the molecular formula is C8H8ClNO2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Aminomethyl-7-chloro-1,3-benzodioxole hydrochloride with an assay of 95%. This product is not supplied as USP, BP, or EP grade and is intended for laboratory and research use only.
How should this chemical be handled safely?
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This compound is classified as a Warning with hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust.
How is this product typically shipped and exported?
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Tech Serve Solutions, as a specialist global supplier, exports chemicals worldwide. Packaging and shipping adhere to international regulations for chemical transport.
How can I request a sample or quote?
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To request a sample or quote for 5-Aminomethyl-7-chloro-1,3-benzodioxole hydrochloride, please contact our sales team through the website or via direct inquiry, providing your details and required quantity.
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