4-Methylumbelliferyl N-acetyl-β-D-glucosaminide
4-Methylumbelliferyl N-acetyl-β-D-glucosaminide (CAS: 37067-30-4) is a fluorogenic substrate with the molecular formula C18H21NO8. It is primarily used in biochemical research for the detection and quantification of N-acetyl-β-D-glucosaminidase activity. This compound emits fluorescence upon enzymatic cleavage, making it valuable for enzyme assays in various biological and diagnostic studies.
- IUPAC
- 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside
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Enzyme Activity Assays
This compound serves as a sensitive fluorogenic substrate for N-acetyl-β-D-glucosaminidase. Its enzymatic hydrolysis releases 4-methylumbelliferone, enabling the quantification of enzyme activity in biological samples.
Biochemical Research
It is utilized in studies involving glycosidases and carbohydrate metabolism. Researchers employ this substrate to investigate enzyme kinetics, inhibition, and function in various cellular and molecular contexts.
Diagnostic Development
The fluorescence properties of 4-Methylumbelliferyl N-acetyl-β-D-glucosaminide make it suitable for developing diagnostic assays. Its detection can be correlated with specific physiological or pathological conditions involving N-acetyl-β-D-glucosaminidase.
| Molecular weight | 379.36 |
|---|---|
| Empirical formula | C18H21NO8 |
| Assay | ≥99.0% (TLC) |
| Solubility | DMF: soluble20 mg/mL, clear, colorless |
| Storage temperature | −20°C |
| Impurities tested | ≤0.1% free 4-methylumbelliferone |
| Suitability | suitable for fluorescence |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 317 nm (pH 10.0)λex 365 nm; λem 445 nm in aqueous buffer pH 5.0 (after cleavage by β-N-acetylglucosaminidase) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methylumbelliferyl N-acetyl-β-D-glucosaminide used for?
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4-Methylumbelliferyl N-acetyl-β-D-glucosaminide is a fluorogenic substrate used for the detection and quantification of N-acetyl-β-D-glucosaminidase activity in biochemical research and diagnostic assays.
What are the CAS number and formula for 4-Methylumbelliferyl N-acetyl-β-D-glucosaminide?
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The CAS number is 37067-30-4 (anhydrous) and the empirical formula is C18H21NO8.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methylumbelliferyl N-acetyl-β-D-glucosaminide with an assay of ≥99.0% (TLC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations?
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Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used when handling this chemical. It carries a WGK Germany rating of 3.
How is this product packed and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring appropriate packaging and adherence to export regulations for safe and secure worldwide delivery.
How can I request a sample or quote?
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Please contact our sales team via the website or direct inquiry to request a sample or a quotation for 4-Methylumbelliferyl N-acetyl-β-D-glucosaminide.
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