4-Methylbenzylmagnesium chloride solution
4-Methylbenzylmagnesium chloride solution (CAS: 29875-07-8), with the linear formula C<sub>6</sub>H<sub>4</sub>CH<sub>3</sub>CH<sub>2</sub>MgCl and a molecular weight of 164.92 g/mol, is a valuable organometallic reagent. Supplied as a 0.5 M solution in THF, this Grignard reagent is primarily utilised in organic synthesis for carbon-carbon bond formation and the introduction of the 4-methylbenzyl group into various molecules. Its reactivity makes it a key intermediate in the preparation of complex organic compounds.
Organometallic Synthesis
Serves as a nucleophilic source of the 4-methylbenzyl group in Grignard reactions, facilitating the formation of new carbon-carbon bonds with electrophiles like aldehydes, ketones, and esters.
Pharmaceutical Intermediate Preparation
A crucial building block in the multi-step synthesis of active pharmaceutical ingredients (APIs) and complex organic molecules where the 4-methylbenzyl moiety is required.
Fine Chemical Manufacturing
Employed in the production of specialty chemicals, agrochemicals, and advanced materials that require precise structural incorporation of the 4-methylbenzyl unit.
| Molecular weight | 164.92 |
|---|---|
| Linear formula | C6H4CH3CH2MgCl |
| Boiling point | 65 °C(lit.) |
| Density | 0.918 g/mL at 25 °C(lit.) |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H261In contact with water releases flammable gas
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P422
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37/38-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methylbenzylmagnesium chloride solution used for?
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4-Methylbenzylmagnesium chloride solution (CAS: 29875-07-8) is primarily used in organic synthesis for forming carbon-carbon bonds and introducing the 4-methylbenzyl group into molecules, particularly in the preparation of pharmaceutical intermediates and fine chemicals.
What is the CAS number and formula for 4-Methylbenzylmagnesium chloride solution?
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The CAS number is 29875-07-8, and the linear formula is C<sub>6</sub>H<sub>4</sub>CH<sub>3</sub>CH<sub>2</sub>MgCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methylbenzylmagnesium chloride solution as a 0.5 M concentration in THF. We do not represent this product as USP, BP, or EP grade; it is suitable for research and general chemical synthesis purposes.
What are the main safety and handling considerations?
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This compound is highly flammable (Flash Point: -17 °C), pyrophoric, and corrosive. It reacts violently with water and can cause severe skin burns and eye damage. Inhalation may cause respiratory irritation. It may also form explosive peroxides. Handle with extreme care in a well-ventilated area, away from ignition sources and incompatible materials. Always wear appropriate personal protective equipment (PPE) including gloves, eye protection, and protective clothing.
How is 4-Methylbenzylmagnesium chloride solution packed and shipped?
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As a regulated hazardous material (UN 2924, Class 8(3), PG II), it is securely packaged according to international shipping regulations and exported with all necessary documentation.
How can I request a sample or quote?
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To request a sample or a quote for 4-Methylbenzylmagnesium chloride solution, please contact our sales team through the website or by calling our direct line.
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