4-Methyl-3-nitrophenol
4-Methyl-3-nitrophenol (CAS: 2042-14-0, Formula: CH3C6H3(NO2)OH, MW: 153.14) is a nitro-substituted phenol derivative. This chemical is primarily utilised as a building block in organic synthesis and as a standard in analytical chemistry for the determination of nitrophenols. It is a key intermediate for creating more complex organic molecules. Tech Serve Solutions offers this compound for research and industrial applications, adhering to stringent quality controls.
- IUPAC
- 3-Nitro-4-methylphenol,3-Nitro-p-cresol,4-Hydroxy-2-nitrotoluene,4-Methyl-5-nitrophenol,NSC 41205
- Synonyms
- 3-Nitro-4-methylphenol3-Nitro-p-cresol4-Hydroxy-2-nitrotoluene4-Methyl-5-nitrophenolNSC 41205

Analytical Standard
4-Methyl-3-nitrophenol serves as a reference standard in analytical procedures. It is specifically used during the determination of nitrophenols, ensuring accuracy and reliability in environmental and chemical testing.
Organic Synthesis Intermediate
This compound is employed as a starting reagent in the synthesis of various organic molecules. For instance, it has been used in the preparation of protected nitrotoluene derivatives, facilitating further chemical transformations.
Chemical Building Block
As a functionalised aromatic compound, 4-Methyl-3-nitrophenol is a valuable building block. Its nitro and hydroxyl groups allow for diverse chemical modifications and incorporation into larger molecular structures.
| Molecular weight | 153.14 |
|---|---|
| Linear formula | CH3C6H3(NO2)OH |
| Application | 4-Methyl-3-nitrophenol was used as standard during the determination of nitrophenols1. It was used as starting reagent during the synthesis of 1-methyl-2-nitro-4-(tetrahydropyranyloxy)benzene2. |
| Melting point | 78-81 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2446 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methyl-3-nitrophenol used for?
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4-Methyl-3-nitrophenol is used as a standard for determining nitrophenols and as a starting reagent in organic synthesis, such as for preparing 1-methyl-2-nitro-4-(tetrahydropyranyloxy)benzene.
What is the CAS number and formula for 4-Methyl-3-nitrophenol?
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The CAS number is 2042-14-0 and the chemical formula is CH3C6H3(NO2)OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methyl-3-nitrophenol in a technical/research grade. We do not represent it as USP, BP, EP or other pharmacopoeia grades unless explicitly stated in the product specifications.
How should 4-Methyl-3-nitrophenol be handled safely?
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4-Methyl-3-nitrophenol is classified with GHS07 symbol and a 'Warning' signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 or equivalent), in a well-ventilated area.
Is 4-Methyl-3-nitrophenol a controlled substance?
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Based on the provided data, there is no indication that 4-Methyl-3-nitrophenol is a controlled substance.
How is 4-Methyl-3-nitrophenol packed and shipped?
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4-Methyl-3-nitrophenol is shipped according to relevant transport regulations, such as UN 2446 for Class 6.1 substances, in appropriate packaging suitable for international export by Tech Serve Solutions.
How can I request a sample or quote for 4-Methyl-3-nitrophenol?
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To request a sample or a quote for 4-Methyl-3-nitrophenol, please contact the Tech Serve Solutions sales team via our website or direct contact details.
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