3,3-Difluoroazetidine hydrochloride
3,3-Difluoroazetidine hydrochloride (CAS: 288315-03-7) is a valuable heterocyclic building block with the molecular formula C3H5F2N · HCl and a molecular weight of 129.54 g/mol. Its unique difluoroazetidine structure makes it an important intermediate in organic synthesis. This compound is primarily used in the development of novel pharmaceuticals and agrochemicals, offering a reactive scaffold for introducing fluorinated heterocyclic motifs into target molecules.
- Synonyms
- C3H5F2N · HCl

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) where the difluoroazetidine moiety can impart desirable pharmacokinetic properties or influence biological activity.
Agrochemical Development
Serves as a key building block for the creation of new pesticides, herbicides, and fungicides, leveraging its fluorinated heterocyclic structure for enhanced efficacy.
Organic Synthesis Reagent
Employed as a versatile reagent in complex organic transformations, facilitating the introduction of fluorinated azetidine rings into diverse molecular architectures.
Materials Science Research
Explored for potential applications in the development of novel fluorinated polymers or functional materials, owing to the unique properties conferred by the fluorine atoms.
| Molecular weight | 129.54 |
|---|---|
| Empirical formula | C3H5F2N · HCl |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 138-143 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,3-Difluoroazetidine hydrochloride used for?
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3,3-Difluoroazetidine hydrochloride is used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals.
What is the CAS number and molecular formula for 3,3-Difluoroazetidine hydrochloride?
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The CAS number is 288315-03-7, and the molecular formula is C3H5F2N · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,3-Difluoroazetidine hydrochloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade; it is supplied for research and development purposes.
How should 3,3-Difluoroazetidine hydrochloride be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust. Ensure good ventilation. Store at 2-8°C. This compound is classified as an irritant to skin, eyes, and respiratory tract.
Is 3,3-Difluoroazetidine hydrochloride a controlled substance?
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The provided data does not indicate that 3,3-Difluoroazetidine hydrochloride is a controlled substance.
How is 3,3-Difluoroazetidine hydrochloride shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific shipping and export details will be provided upon inquiry.
How can I request a quote or sample for 3,3-Difluoroazetidine hydrochloride?
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Please contact Tech Serve Solutions directly through our website or sales department to request a quote or sample.
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