3,3-Difluoro-2-(2-pyrrolidinylmethyl)acrylic acid
3,3-Difluoro-2-(2-pyrrolidinylmethyl)acrylic acid (CAS: 870703-86-9) is a fluorinated heterocyclic building block with the molecular formula C8H11F2NO2 and a molecular weight of 191.18 g/mol. This compound is valuable in organic synthesis, particularly for introducing difluorinated pyrrolidine moieties into complex molecules. Its unique structure makes it a key intermediate for the development of novel pharmaceuticals and agrochemicals, offering enhanced metabolic stability and lipophilicity.
- Synonyms
- C8H11F2NO2
Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) where the incorporation of fluorine atoms can modulate pharmacokinetic properties such as bioavailability and metabolic stability. The pyrrolidine ring offers a scaffold for further functionalisation.
Agrochemical Development
Serves as a building block for new agrochemical compounds. The presence of fluorine can improve the efficacy and environmental profile of pesticides and herbicides, enhancing their interaction with biological targets.
Organic Synthesis Reagent
A versatile reagent for introducing difluorinated heterocyclic fragments in complex organic molecules. It is employed in research and development settings for creating novel chemical entities.
| Molecular weight | 191.18 |
|---|---|
| Empirical formula | C8H11F2NO2 |
| Refractive index | n20/D 1.4916(lit.) |
Hazard statements
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,3-Difluoro-2-(2-pyrrolidinylmethyl)acrylic acid used for?
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This compound is primarily used as a building block in organic synthesis, particularly for creating fluorinated heterocyclic compounds relevant to pharmaceutical and agrochemical research and development.
What are the CAS number and molecular formula?
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The CAS number is 870703-86-9, and the molecular formula is C8H11F2NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific grade and purity should be confirmed with our sales team, as we do not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should 3,3-Difluoro-2-(2-pyrrolidinylmethyl)acrylic acid be handled safely?
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This compound is classified as hazardous. It may cause skin irritation and serious eye irritation (H317, H319). Appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, face shields, and gloves, should be used. Handle in a well-ventilated area.
How is this chemical packed and shipped?
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Products are carefully packed according to international shipping regulations to ensure safe transit. Tech Serve Solutions is a global supplier and exporter, accustomed to handling complex logistical requirements for chemicals worldwide.
How can I request a sample or quote?
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To request a sample or a quotation for 3,3-Difluoro-2-(2-pyrrolidinylmethyl)acrylic acid, please contact our sales department via the website or direct email, providing your contact details and the quantity required.
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