3,3-Difluoropiperidine hydrochloride
3,3-Difluoropiperidine hydrochloride (CAS: 496807-97-7) is a fluorinated heterocyclic compound with a molecular weight of 157.59 g/mol. This building block is characterised by its difluorinated piperidine ring and is primarily utilised in chemical synthesis. Its specific structural features make it a valuable intermediate for the development of novel molecules within the pharmaceutical and agrochemical industries, contributing to the creation of advanced materials and specialised compounds.
- Synonyms
- C5H9F2N · HCl

Pharmaceutical Intermediate
This compound serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs). The incorporation of the difluoropiperidine moiety can influence the pharmacokinetic and pharmacodynamic properties of drug candidates.
Agrochemical Development
It is employed in the research and development of new agrochemicals. The fluorine atoms can impart unique properties, potentially enhancing efficacy or stability in crop protection agents.
Organic Synthesis
As a specialised heterocyclic building block, 3,3-Difluoropiperidine hydrochloride is used in complex organic synthesis pathways. It enables the introduction of a difluorinated piperidine ring into target molecules.
Material Science Research
The unique chemical structure may find applications in the development of advanced materials where specific electronic or physical properties are desired.
| Molecular weight | 157.59 |
|---|---|
| Empirical formula | C5H9F2N · HCl |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 243-247 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,3-Difluoropiperidine hydrochloride used for?
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3,3-Difluoropiperidine hydrochloride is primarily used as a building block in organic synthesis, particularly for the development of pharmaceutical intermediates and agrochemicals. Its difluorinated piperidine structure is valuable for introducing specific chemical properties into target molecules.
What is the CAS number and chemical formula for 3,3-Difluoropiperidine hydrochloride?
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The CAS number is 496807-97-7, and its empirical formula (as indicated by the synonym) is C5H9F2N · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,3-Difluoropiperidine hydrochloride with a minimum assay of 97%. This product is typically considered a research or technical grade chemical and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 3,3-Difluoropiperidine hydrochloride be handled safely?
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According to GHS classifications, this compound is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (e.g., type N95). Ensure good ventilation and avoid inhalation of dust.
How is this chemical packed, shipped, and exported?
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3,3-Difluoropiperidine hydrochloride is carefully packed to ensure product integrity during transit. As a global supplier, Tech Serve Solutions has extensive experience in exporting chemicals worldwide, adhering to all relevant shipping regulations.
How can I request a quote or sample for 3,3-Difluoropiperidine hydrochloride?
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To request a quote or a sample, please visit the Tech Serve Solutions website or contact our sales department directly. Our team will be pleased to assist you with your inquiry.
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