4-Methoxycarbonylphenyl chloroformate
4-Methoxycarbonylphenyl chloroformate (CAS: 31140-40-6, C9H7ClO4) is a key chemical intermediate with a molecular weight of 214.60. This compound serves primarily as a protecting and derivatizing reagent in organic synthesis, particularly valuable in peptide chemistry and for amine protection. Its reactive chloroformate group enables selective functionalization, making it an indispensable tool for chemists in various research and development settings.
- IUPAC
- Methyl 4-chlorocarbonyloxybenzoate
- Synonyms
- Methyl 4-chlorocarbonyloxybenzoate

Amine Protection
Utilised for the selective protection of amine groups during multi-step organic syntheses. This protection prevents unwanted side reactions of the amine functionality.
Peptide Synthesis
Acts as a reagent in the synthesis of peptides, contributing to the controlled coupling of amino acids. Its application aids in the construction of complex peptide chains.
Chemical Synthesis
Serves as a versatile building block in the synthesis of diverse organic molecules. Its reactive nature allows for the introduction of specific functional groups.
Derivatizing Agent
Employed to introduce specific derivatives, thereby altering the properties of molecules for analysis or further reaction. This is crucial in analytical chemistry and material science.
| Molecular weight | 214.60 |
|---|---|
| Empirical formula | C9H7ClO4 |
| Assay | ≥98.5% (AT) |
| Boiling point | 103-106 °C/4 mmHg(lit.) |
| Storage temperature | 2-8°C |
| Melting point | 51-54 °C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methoxycarbonylphenyl chloroformate used for?
+
4-Methoxycarbonylphenyl chloroformate is primarily used for amine protection and as a derivatizing reagent in chemical synthesis, notably in peptide chemistry.
What are the CAS number and formula for 4-Methoxycarbonylphenyl chloroformate?
+
The CAS number is 31140-40-6 and the empirical formula is C9H7ClO4.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 4-Methoxycarbonylphenyl chloroformate with an assay of ≥98.5% (AT). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary safety hazards associated with this chemical?
+
This compound is classified as Danger, indicated by GHS05. It causes severe skin burns and eye damage (H314). Handling requires appropriate personal protective equipment, including chemical-resistant gloves, eye protection (eyeshields, face shield), and respiratory protection.
How is 4-Methoxycarbonylphenyl chloroformate packed and shipped?
+
The product is shipped under UN 3261, Class 8, Packing Group II. Storage is recommended at 2-8°C. TSS is a specialist global supplier and exporter.
How can I request a sample or quote for 4-Methoxycarbonylphenyl chloroformate?
+
Please contact our sales team directly via our website or by phone to request a sample or a quotation for 4-Methoxycarbonylphenyl chloroformate.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis