4-Methoxybenzylmagnesium chloride solution
4-Methoxybenzylmagnesium chloride solution (CAS 38769-92-5), with the linear formula C8H9ClMgO, is a Grignard reagent supplied by Tech Serve Solutions. Its molecular weight is 180.91 g/mol. This organometallic compound is primarily utilised in chemical synthesis, acting as a versatile building block for introducing the 4-methoxybenzyl group into organic molecules. It is provided as a 0.25 M solution in Tetrahydrofuran (THF).

Organic Synthesis Reagent
As a Grignard reagent, 4-Methoxybenzylmagnesium chloride is employed in carbon-carbon bond formation reactions. It readily reacts with electrophiles such as aldehydes, ketones, esters, and epoxides to create new functionalised organic molecules.
Intermediate in Pharmaceutical Chemistry
The 4-methoxybenzyl moiety is present in various pharmacologically active compounds. This reagent serves as a key intermediate for the synthesis of complex drug molecules and their precursors.
Precursor for Fine Chemicals
This Grignard solution can be used in the preparation of a range of fine chemicals and speciality materials where the 4-methoxybenzyl group is a desired structural component.
| Molecular weight | 180.91 |
|---|---|
| Linear formula | CH3OC6H4CH2MgCl |
| Boiling point | 65 °C |
| Density | 0.914 g/mL at 25 °C |
| Concentration | 0.25 M in THF |
| Storage temperature | 2-8°C |




Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methoxybenzylmagnesium chloride solution used for?
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4-Methoxybenzylmagnesium chloride solution (CAS 38769-92-5) is primarily used as a Grignard reagent in organic synthesis for forming carbon-carbon bonds and as an intermediate in the preparation of pharmaceuticals and fine chemicals.
What is the CAS number and formula for 4-Methoxybenzylmagnesium chloride solution?
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The CAS number is 38769-92-5 and the linear formula is CH3OC6H4CH2MgCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methoxybenzylmagnesium chloride solution as a 0.25 M concentration in THF. We do not represent this product as USP, BP, or EP grade.
What are the main hazards associated with this product?
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This product is highly flammable (H225), causes skin irritation (H315), serious eye damage (H318), and may cause respiratory irritation (H335). It is also suspected of causing cancer (H351). It may form explosive peroxides. Handle with extreme care in a well-ventilated area, away from ignition sources, and wear appropriate personal protective equipment.
How is this chemical packed, shipped, and exported?
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This chemical is packed and shipped according to international regulations for hazardous materials, including UN 2924, Hazard Class 8(3), Packing Group II. Tech Serve Solutions is experienced in global export.
How can I request a sample or quote?
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To request a sample or a quotation for 4-Methoxybenzylmagnesium chloride solution, please contact our sales team through the website or by phone.
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