4-Methoxybenzamidine
4-Methoxybenzamidine (CAS: 22265-37-8), with the molecular formula C8H10N2O and a molecular weight of 150.18 g/mol, is a fine chemical supplied by Tech Serve Solutions. It functions as a valuable reagent, particularly in the postcolumn derivatisation for the high-performance liquid chromatography (HPLC) determination of reducing carbohydrates and glycoproteins. Its fluorescence properties after derivatisation make it suitable for sensitive analytical applications.
- IUPAC
- 4-Amidinoanisole
- Synonyms
- 4-Amidinoanisole
HPLC Reagent for Carbohydrate Analysis
4-Methoxybenzamidine serves as a reagent for the determination of reducing carbohydrates and glycoproteins. It is used in postcolumn derivatisation techniques after HPLC separation, enabling sensitive detection.
Fluorescence Derivatisation
This compound is suitable for fluorescence detection when derivatised. Upon reaction with carbohydrates, it exhibits specific excitation and emission wavelengths (λex 393 nm; λem 478 nm), facilitating quantification.
Improvement of Benzamidine Methods
Utilisation of 4-Methoxybenzamidine can lead to improvements in analytical methods previously employing benzamidine, offering enhanced sensitivity or specificity for certain analytes.
| Molecular weight | 150.18 |
|---|---|
| Empirical formula | C8H10N2O |
| Assay | ≥96.0% (NT) |
| Application | Reagent for the determination of reducing carbohydrates and glycoproteins by postcolumn derivatization after HPLC1,2; A method using benzamidine should be improved by this reagent3 |
| Suitability | suitable for fluorescence |
| Melting point | 119-124 °C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3263 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 393 nm; λem 478 nm (after derivatization with glucose)λex 393 nm; λem 478 nm(lit.) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methoxybenzamidine used for?
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4-Methoxybenzamidine is used as a reagent in high-performance liquid chromatography (HPLC) for the postcolumn derivatisation and determination of reducing carbohydrates and glycoproteins. It is also suitable for fluorescence detection after derivatisation.
What are the CAS number and formula for 4-Methoxybenzamidine?
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The CAS number for 4-Methoxybenzamidine is 22265-37-8, and its molecular formula is C8H10N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methoxybenzamidine with an assay of ≥96.0% (NT). We do not represent this product as USP, BP, or EP grade.
What are the safety considerations for handling 4-Methoxybenzamidine?
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4-Methoxybenzamidine is classified as Danger (GHS05) and carries the hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including eyeshields, face shields, and chemical-resistant gloves, must be worn. Ensure adequate ventilation and refer to the Safety Data Sheet for full handling instructions.
How is 4-Methoxybenzamidine packed and exported?
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Tech Serve Solutions can pack and export 4-Methoxybenzamidine globally, adhering to all relevant shipping regulations for hazardous materials (UN 3263, Class 8, PG III).
How can I request a quote or sample for 4-Methoxybenzamidine?
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To request a quote or sample of 4-Methoxybenzamidine, please contact our sales department via the website or email, providing your specific requirements and shipping details.
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