4-Fluorophenyl isothiocyanate
4-Fluorophenyl isothiocyanate (CAS: 1544-68-9, Formula: FC6H4NCS) is a fluorinated organic building block with a molecular weight of 153.18 g/mol. This compound is primarily utilised in chemical synthesis, serving as a key intermediate for the creation of various organic molecules. Its utility lies in its ability to introduce the 4-fluorophenyl isothiocyanate moiety into more complex structures, finding applications in the development of thiourea derivatives and other specialised chemical compounds. It is supplied with an assay of 98%.
Synthesis of Thiourea Derivatives
4-Fluorophenyl isothiocyanate is employed in organic synthesis for the preparation of diverse thiourea derivatives. These compounds can serve as intermediates in the development of pharmaceuticals and other fine chemicals.
Preparation of Heterocyclic Compounds
This isothiocyanate can be used as a building block in the construction of various heterocyclic ring systems. Its reactive nature allows for cyclisation reactions, leading to complex molecular architectures.
Reagent in Organic Chemistry
As a fluorinated building block, 4-Fluorophenyl isothiocyanate is a valuable reagent for introducing fluorine atoms and the isothiocyanate group into organic molecules, facilitating the synthesis of fluorinated compounds with potentially unique properties.
| Molecular weight | 153.18 |
|---|---|
| Linear formula | FC6H4NCS |
| Assay | 98% |
| Boiling point | 228 °C(lit.) |
| Storage temperature | 2-8°C |
| Application | 4-Fluorophenyl isothiocyanate has been used in the synthesis of thiourea derivatives1. It has also been used in the preparation of -(4-phenylsulfonyl)-benzoic acid hydrazide. |
| Melting point | 24-26 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
- H317May cause an allergic skin reaction
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 89 °C / 192.2 °F |
| Transport (UN / ADR) | UN 1759 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-42 |
| Safety statements (S) | 23-26-36/37-39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluorophenyl isothiocyanate used for?
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4-Fluorophenyl isothiocyanate is primarily used as a building block in chemical synthesis, particularly for creating thiourea derivatives and other fluorinated organic compounds.
What are the CAS number and formula for 4-Fluorophenyl isothiocyanate?
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The CAS number for 4-Fluorophenyl isothiocyanate is 1544-68-9, and its chemical formula is FC6H4NCS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluorophenyl isothiocyanate with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-Fluorophenyl isothiocyanate be handled and stored?
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Due to its corrosive nature (H314), potential to cause allergic skin reaction (H317), and risk of allergy or asthma symptoms or breathing difficulties if inhaled (H334), handle 4-Fluorophenyl isothiocyanate with appropriate personal protective equipment, including eyeshields, face shields, and suitable gloves and respirators. Store in a cool, well-ventilated area, ideally under refrigeration at 2-8°C.
Is 4-Fluorophenyl isothiocyanate packed and shipped internationally by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Fluorophenyl isothiocyanate.
How can I request a quote or sample of 4-Fluorophenyl isothiocyanate?
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To request a quote or sample, please contact the Tech Serve Solutions sales team via our website or direct enquiry channels.
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